Schumacher Pia Madeleine, Kaune Almuth, Merkenschlager Andreas, Bernhard Matthias Karl, Kiess Wieland, Neininger Martina Patrizia, Bertsche Astrid, Bertsche Thilo
Drug Safety Center and Dept. of Clinical Pharmacy, Leipzig University, Brüderstraße 32, 04103 Leipzig, Germany.
University Hospital for Children and Adolescents, Centre of Pediatric Research, Liebigstraße 20a, 04103 Leipzig, Germany.
Epilepsy Behav. 2018 Jul;84:37-43. doi: 10.1016/j.yebeh.2018.02.032. Epub 2018 May 7.
Parents of children with epilepsy are at risk of committing high-risk handling errors with a high potential to harm the patient when administering anticonvulsant rescue medication. We developed a training concept addressing identified high-risk handling errors and investigated its effects on parents' skills.
In a controlled prospective intervention study, parents of children with epilepsy were asked to demonstrate their administration of rescue medication by using dummy dolls. A clinical pharmacist monitored rectal or buccal administration and addressed errors in the intervention group with training and information sheets. Three to 6weeks later, intervention's sustainability was assessed at a home visit.
One hundred sixty-one parents completed full study assessment: 92 in the intervention group and 69 in the control group. The number of processes with at least one handling error was reduced from 96.4% to 56.7% in rectal tube administration and from 66.7% to 13.5% in buccal administration (both p<0.001).
A one-time intervention for parents significantly and sustainably reduced high-risk handling errors. Dummy dolls and information sheet were adequate for an effective and feasible training to support the correct administration of anticonvulsant rescue medication.
癫痫患儿的家长在使用抗惊厥急救药物时，有犯下高风险操作错误的风险，而这些错误极有可能对患儿造成伤害。我们制定了一个针对已识别出的高风险操作错误的培训方案，并研究了其对家长技能的影响。
在一项对照前瞻性干预研究中，要求癫痫患儿的家长使用仿真娃娃演示他们给予急救药物的过程。一名临床药剂师监测直肠或口腔给药情况，并通过培训和信息表对干预组的错误进行纠正。三至六周后，通过家访评估干预措施的可持续性。
161名家长完成了全面的研究评估：干预组92名，对照组69名。直肠给药时，至少出现一处操作错误的流程数量从96.4%降至56.7%，口腔给药时从66.7%降至13.5%（两者p<0.001）。
对家长进行的一次性干预显著且可持续地减少了高风险操作错误。仿真娃娃和信息表对于有效且可行的培训是足够的，有助于正确给予抗惊厥急救药物。
