Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain (FMRIB), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands.
Elife. 2018 May 11;7:e35237. doi: 10.7554/eLife.35237.
Comparing the brains of related species faces the challenges of establishing homologies whilst accommodating evolutionary specializations. Here we propose a general framework for understanding similarities and differences between the brains of primates. The approach uses white matter blueprints of the whole cortex based on a set of white matter tracts that can be anatomically matched across species. The blueprints provide a common reference space that allows us to navigate between brains of different species, identify homologous cortical areas, or to transform whole cortical maps from one species to the other. Specializations are cast within this framework as deviations between the species' blueprints. We illustrate how this approach can be used to compare human and macaque brains.
比较相关物种的大脑面临着在适应进化特化的同时建立同源性的挑战。在这里，我们提出了一个理解灵长类动物大脑之间相似性和差异性的通用框架。该方法使用基于一组可以在物种间进行解剖匹配的白质束的整个皮质的白质蓝图。这些蓝图提供了一个通用的参考空间，使我们能够在不同物种的大脑之间导航，识别同源的皮质区域，或者将整个皮质图谱从一个物种转换到另一个物种。在这个框架内，特化被视为物种蓝图之间的偏差。我们说明了如何使用这种方法来比较人类和猕猴的大脑。
