Instituto de Física, Universidade Federal do Rio Grande do Sul (UFRGS), CP: 15051 Porto Alegre, RS, Brazil.
J Phys Condens Matter. 2018 Jun 27;30(25):255101. doi: 10.1088/1361-648X/aac40b. Epub 2018 May 11.
Assuming the selectivity filter of KcsA potassium ion channel may exhibit quantum coherence, we extend a previous model by Vaziri and Plenio (2010 New J. Phys. 12 085001) to take into account Coulomb repulsion between potassium ions. We show that typical ion transit timescales are determined by this interaction, which imposes optimal input/output parameter ranges. Also, as observed in other examples of quantum tunneling in biological systems, the addition of moderate noise helps coherent ion transport.
假设 KcsA 钾离子通道的选择性过滤器可能表现出量子相干性,我们扩展了 Vaziri 和 Plenio(2010 年《新物理学杂志》12 卷 085001 号)之前的模型,以考虑钾离子之间的库仑斥力。我们表明,典型的离子传输时间尺度由这种相互作用决定,它施加了最佳的输入/输出参数范围。此外,正如在生物系统中其他量子隧穿的例子中观察到的那样,适度噪声的添加有助于相干离子输运。