• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

镁硫酸盐可减少肥胖患者行袖状胃切除术的阿片类药物用量:一项前瞻性、随机临床试验。

Magnesium Sulfate Reduced Opioid Consumption in Obese Patients Undergoing Sleeve Gastrectomy: a Prospective, Randomized Clinical Trial.

机构信息

Department of Anesthesiology and Reanimation, School of Medicine, Yeditepe University, Istanbul, Turkey.

出版信息

Obes Surg. 2018 Sep;28(9):2783-2788. doi: 10.1007/s11695-018-3243-7.

DOI:10.1007/s11695-018-3243-7
PMID:29754384
Abstract

OBJECTIVE

The purpose of the study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation.

DESIGN

A prospective, randomized, placebo-controlled clinical study.

SETTING

University hospital.

PARTICIPANTS

Eighty patients undergoing sleeve gastrectomy.

MEASUREMENTS AND MAIN RESULTS

Visual analog scale for the evaluation of pain, sedation score, mean arterial pressure, heart rate, and total analgesic consumption was recorded. Serum magnesium levels were determined before the operation, at the end of the operation, and at 24 h. There were no significant differences between the groups with respect to demographics, and sedation scores. Cumulative morphine consumption and pain scores were found to be higher in the control group than the magnesium group.

CONCLUSION

Perioperative use of magnesium sulfate reduced postoperative pain and opioid consumption in obese patients undergoing sleeve gastrectomy operations.

摘要

目的

本研究旨在探讨硫酸镁对袖状胃切除术术后疼痛管理的影响。

设计

前瞻性、随机、安慰剂对照的临床研究。

地点

大学医院。

参与者

80 例行袖状胃切除术的患者。

测量和主要结果

采用视觉模拟评分法评估疼痛、镇静评分、平均动脉压、心率和总镇痛药物消耗量。分别于术前、术毕和术后 24 小时测定血清镁水平。两组患者在人口统计学特征和镇静评分方面无显著差异。对照组的累积吗啡消耗量和疼痛评分均高于镁组。

结论

肥胖患者在行袖状胃切除术时,围手术期使用硫酸镁可减轻术后疼痛和阿片类药物的消耗。

相似文献

1
Magnesium Sulfate Reduced Opioid Consumption in Obese Patients Undergoing Sleeve Gastrectomy: a Prospective, Randomized Clinical Trial.镁硫酸盐可减少肥胖患者行袖状胃切除术的阿片类药物用量:一项前瞻性、随机临床试验。
Obes Surg. 2018 Sep;28(9):2783-2788. doi: 10.1007/s11695-018-3243-7.
2
Role of magnesium sulfate in postoperative pain management for patients undergoing thoracotomy.硫酸镁在开胸手术患者术后疼痛管理中的作用。
J Cardiothorac Vasc Anesth. 2007 Dec;21(6):827-31. doi: 10.1053/j.jvca.2006.11.013. Epub 2007 Feb 7.
3
Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial.静脉注射布洛芬和对乙酰氨基酚在肥胖症手术多模式术后疼痛管理中的比较:一项随机对照试验。
J Clin Anesth. 2018 Nov;50:5-11. doi: 10.1016/j.jclinane.2018.06.030. Epub 2018 Jun 20.
4
Magnesium sulfate improves postoperative analgesia in laparoscopic gynecologic surgeries: a double-blind randomized controlled trial.硫酸镁改善腹腔镜妇科手术的术后镇痛效果:一项双盲随机对照试验。
J Clin Anesth. 2016 Nov;34:379-84. doi: 10.1016/j.jclinane.2016.05.006. Epub 2016 Jun 5.
5
Analgesic efficacy of ketamine and magnesium after laparoscopic sleeve gastrectomy: A randomized, double-blind, placebo-controlled trial.腹腔镜袖状胃切除术术后氯胺酮和镁的镇痛效果:一项随机、双盲、安慰剂对照试验。
J Clin Anesth. 2021 Feb;68:110097. doi: 10.1016/j.jclinane.2020.110097. Epub 2020 Oct 23.
6
Efficacy of Magnesium Sulfate Added to Local Anesthetic in a Transversus Abdominis Plane Block for Analgesia Following Total Abdominal Hysterectomy: A Randomized Trial.硫酸镁复合局麻药行腹横肌平面阻滞用于全子宫切除术后镇痛的随机对照研究。
Pain Physician. 2017 Nov;20(7):641-647.
7
Prospective randomized double-blind controlled trial of continuous local anesthetic infusion to reduce narcotic use in laparoscopic sleeve gastrectomy.连续局部麻醉药输注减少腹腔镜袖状胃切除术麻醉剂使用的前瞻性随机双盲对照试验
Surg Obes Relat Dis. 2015 Sep-Oct;11(5):1152-6. doi: 10.1016/j.soard.2014.12.030. Epub 2015 Jan 6.
8
A comparative study with oral nifedipine, intravenous nimodipine, and magnesium sulfate in postoperative analgesia.硝苯地平口服制剂、尼莫地平静脉制剂与硫酸镁用于术后镇痛的比较研究。
Anesth Analg. 2000 Oct;91(4):938-43. doi: 10.1097/00000539-200010000-00032.
9
An enhanced recovery program for bariatric surgical patients significantly reduces perioperative opioid consumption and postoperative nausea.减重手术患者的强化康复方案可显著减少围手术期阿片类药物的消耗和术后恶心。
Surg Obes Relat Dis. 2018 Jun;14(6):849-856. doi: 10.1016/j.soard.2018.02.010. Epub 2018 Feb 13.
10
Comparison of magnesium sulfate with opioid and NSAIDs on postoperative pain management after coronary artery bypass surgery.
J Cardiothorac Vasc Anesth. 2005 Dec;19(6):714-8. doi: 10.1053/j.jvca.2005.08.010.

引用本文的文献

1
Optimal Dose of Magnesium Sulfate Infusion in Obese Patients: A Double-Blind Randomized Trial.肥胖患者硫酸镁输注的最佳剂量:一项双盲随机试验
Anesthesiol Res Pract. 2025 Mar 19;2025:8854830. doi: 10.1155/anrp/8854830. eCollection 2025.
2
Opioid-Free Anesthesia in Bariatric Surgery: Is It the One and Only? A Comprehensive Review of the Current Literature.肥胖症手术中的无阿片类麻醉:它是唯一的选择吗?对当前文献的全面综述。
Healthcare (Basel). 2024 May 27;12(11):1094. doi: 10.3390/healthcare12111094.
3
The Impact of Nutrition on Pain: A Narrative Review of Recent Literature.

本文引用的文献

1
Obstructive sleep apnea and bariatric surgical guidelines: summary and update.阻塞性睡眠呼吸暂停与减重手术指南:总结与更新
Curr Opin Anaesthesiol. 2018 Feb;31(1):104-109. doi: 10.1097/ACO.0000000000000542.
2
The Standardized Postoperative Checklist for Bariatric Surgery; a Tool for Safe Early Discharge?减重手术标准化术后检查表;安全早期出院的工具?
Obes Surg. 2017 Dec;27(12):3102-3109. doi: 10.1007/s11695-017-2746-y.
3
Multimodal analgesia model to achieve low postoperative opioid requirement following bariatric surgery.
营养对疼痛的影响:近期文献的叙述性综述。
Curr Pain Headache Rep. 2024 Oct;28(10):1059-1066. doi: 10.1007/s11916-024-01275-x. Epub 2024 Jun 14.
4
Unravelling the analgesic effects of perioperative magnesium in general abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.揭开普通腹部手术中围手术期镁的镇痛作用之谜:随机对照试验的系统评价和荟萃分析。
Braz J Anesthesiol. 2024 Jul-Aug;74(4):844524. doi: 10.1016/j.bjane.2024.844524. Epub 2024 Jun 5.
5
Oral application of magnesium-L-threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients-A randomized, double-blind, placebo-controlled trial.口服 L-苏糖酸镁可增强晚期癌症患者的镇痛效果并减少阿片类药物的用量:一项随机、双盲、安慰剂对照试验。
Cancer Med. 2023 Feb;12(4):4343-4351. doi: 10.1002/cam4.4922. Epub 2023 Jan 26.
6
Strategy for Calculating Magnesium Sulfate Dose in Obese Patients: A Randomized Blinded Trial.肥胖患者硫酸镁剂量计算策略:一项随机双盲试验
Anesthesiol Res Pract. 2022 Nov 8;2022:8424670. doi: 10.1155/2022/8424670. eCollection 2022.
7
Enhanced recovery after bariatric surgery: an Italian consensus statement.减重手术后的加速康复:意大利共识声明。
Surg Endosc. 2022 Oct;36(10):7171-7186. doi: 10.1007/s00464-022-09498-y. Epub 2022 Aug 11.
8
Comparison of three intraoperative analgesic strategies in laparoscopic bariatric surgery: a retrospective study of immediate postoperative outcomes.三种腹腔镜减重手术术中镇痛策略的比较:一项即刻术后结局的回顾性研究。
Braz J Anesthesiol. 2022 Sep-Oct;72(5):560-566. doi: 10.1016/j.bjane.2021.06.006. Epub 2021 Jun 30.
9
Magnesium for Pain Treatment in 2021? State of the Art.2021 年镁在疼痛治疗中的应用?最新进展。
Nutrients. 2021 Apr 21;13(5):1397. doi: 10.3390/nu13051397.
10
Effect of Magnesium Sulfate Added to Tincture of Opium and Buprenorphine on Pain and Quality of Life in Women with Dysmenorrhea: A Prospective, Randomized, Double-blind, Placebo-controlled Trial.硫酸镁添加于阿片酊和丁丙诺啡对痛经女性疼痛及生活质量的影响:一项前瞻性、随机、双盲、安慰剂对照试验
Addict Health. 2020 Oct;12(4):259-268. doi: 10.22122/ahj.v12i4.285.
用于在减重手术后实现低术后阿片类药物需求量的多模式镇痛模型。
Hong Kong Med J. 2016 Oct;22(5):428-34. doi: 10.12809/hkmj154769. Epub 2016 Jul 15.
4
Morbid obesity and perioperative complications.病态肥胖与围手术期并发症
Curr Opin Anaesthesiol. 2016 Feb;29(1):103-8. doi: 10.1097/ACO.0000000000000279.
5
Effect of low-dose (single-dose) magnesium sulfate on postoperative analgesia in hysterectomy patients receiving balanced general anesthesia.小剂量(单剂量)硫酸镁对接受平衡全身麻醉的子宫切除患者术后镇痛的影响。
Anesthesiol Res Pract. 2015;2015:306145. doi: 10.1155/2015/306145. Epub 2015 Feb 1.
6
Fast-track bariatric surgery improves perioperative care and logistics compared to conventional care.与传统护理相比,快速通道减肥手术改善了围手术期护理和后勤保障。
Obes Surg. 2015 Jan;25(1):28-35. doi: 10.1007/s11695-014-1355-2.
7
Challenges in the optimisation of post-operative pain management with opioids in obese patients: a literature review.肥胖患者术后阿片类药物镇痛优化的挑战:文献综述。
Obes Surg. 2013 Sep;23(9):1458-75. doi: 10.1007/s11695-013-0998-8.
8
Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.围手术期系统镁以最小化术后疼痛:随机对照试验的荟萃分析。
Anesthesiology. 2013 Jul;119(1):178-90. doi: 10.1097/ALN.0b013e318297630d.
9
Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea.志愿者中阻塞性睡眠呼吸暂停高危人群的实验性疼痛和阿片类镇痛药。
PLoS One. 2013;8(1):e54807. doi: 10.1371/journal.pone.0054807. Epub 2013 Jan 29.
10
Peri-operative intravenous administration of magnesium sulphate and postoperative pain: a meta-analysis.围手术期静脉内给予硫酸镁与术后疼痛:荟萃分析。
Anaesthesia. 2013 Jan;68(1):79-90. doi: 10.1111/j.1365-2044.2012.07335.x. Epub 2012 Nov 1.