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埃及艾斯尤特地区注射用避孕药的可接受性

Acceptability of injectable contraceptives in Assiut, Egypt.

作者信息

Salem H T, Salah M, Aly M Y, Thabet A I, Shaaban M M, Fathalla M F

机构信息

Department of Obstetrics and Gynaecology Assiut, Egypt.

出版信息

Contraception. 1988 Dec;38(6):697-710. doi: 10.1016/0010-7824(88)90051-0.

Abstract

The present work was a randomized comparative study of two injectable progestogen-only contraceptives. The first group (200 subjects) received 150 mg of depotmedroxyprogesterone acetate (Depoprovera) every 84 +/- 7 days and the second (200 subjects) received 200 mg of norethisterone enanthate (Noristerat) every 56 +/- 7 days. Acceptors of injectable contraceptives in Assiut, Egypt, were mainly women looking for fertility termination. Menstrual disruption was the main side effect among both treatment groups. Amenorrhoea was the commonest menstrual complaint and was the main reason for discontinuation in both groups. Only one pregnancy occurred during NET-EN use; two more pregnancies occurred, one in each of the two groups but there were indications that conception preceded the first injection. Menstrual irregularities were generally more frequent with DMPA users. However, DMPA had better one-year continuation rates than NET-EN (68.8 +/- 3.5 and 57.1 +/- 3.6 per 100 women, respectively).

摘要

本研究是对两种仅含孕激素的注射用避孕药进行的随机对照研究。第一组(200名受试者)每84±7天接受150毫克醋酸甲羟孕酮长效注射剂(狄波普维拉),第二组(200名受试者)每56±7天接受200毫克庚酸炔诺酮(诺仕妥)。埃及阿斯尤特的注射用避孕药使用者主要是寻求终止妊娠的女性。月经紊乱是两个治疗组的主要副作用。闭经是最常见的月经问题,也是两组停药的主要原因。使用庚酸炔诺酮期间仅发生1例妊娠;另外发生2例妊娠,两组各1例,但有迹象表明受孕发生在首次注射之前。使用醋酸甲羟孕酮的使用者月经不规律通常更频繁。然而,醋酸甲羟孕酮的一年续用率高于庚酸炔诺酮(分别为每100名女性68.8±3.5和57.1±3.6)。

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