初诊癌症患者人群中左胃动脉栓塞术后体重变化分析
Analysis of weight changes after left gastric artery embolization in a cancer-naive population.
作者信息
Kim David J, Raman Hari S, Salter Amber, Ramaswamy Raja, Gunn Andrew J, Weiss Clifford R, Akinwande Olaguoke
机构信息
Division of Interventional Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO, US.
Division of Interventional Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
出版信息
Diagn Interv Radiol. 2018 Mar-Apr;24(2):94-97. doi: 10.5152/dir.2018.17412.
PURPOSE
We aimed to evaluate weight changes after left gastric artery (LGA) embolization in a retrospective cancer-naive cohort.
METHODS
A retrospective study was conducted to identify patients who underwent LGA embolization for gastrointestinal bleeding (GI). Patients with known cancer diagnoses at the time of LGA embolization were excluded. Pre- and postprocedure weights were assessed. Statistical analysis was performed using paired t-test and Wilcoxon signed-rank test.
RESULTS
A total of 39 patients were identified. In 21 patients who had documented pre- and postprocedural weights, a median of 16.3 kg weight loss (P = 0.045) was observed over a median time of 12 months (range, 2-72). In patients who had pre- and postprocedure endoscopies (n=6), 2 had worsening ulcers following LGA embolization and 4 had stable or no abnormal findings.
CONCLUSION
Our preliminary observation suggests that LGA embolization is well tolerated and results in unintended weight loss. Larger studies are needed to confirm these preliminary findings.
目的
我们旨在评估在一个未患癌症的回顾性队列中，胃左动脉（LGA）栓塞术后的体重变化。
方法
进行一项回顾性研究，以确定因胃肠道出血（GI）接受LGA栓塞术的患者。排除在LGA栓塞术时已知患有癌症的患者。评估术前和术后体重。使用配对t检验和Wilcoxon符号秩检验进行统计分析。
结果
共确定39例患者。在21例有术前和术后体重记录的患者中，在中位时间12个月（范围2 - 72个月）内观察到体重中位数下降16.3千克（P = 0.045）。在有术前和术后内镜检查的患者（n = 6）中，2例在LGA栓塞术后溃疡恶化，4例结果稳定或无异常发现。
结论
我们的初步观察表明，LGA栓塞术耐受性良好，并导致意外体重减轻。需要更大规模的研究来证实这些初步发现。
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