Elens S, Roger T, Elens M, Rommens J, Sarafidis A, Capelluto E, Delcour C
Hopital Erasme, Route de Lennik 808, 1070, Brussels, Belgium.
CHIREC Site Delta, Boulevard du Triomphe 201, 1160, Brussels, Belgium.
Cardiovasc Intervent Radiol. 2019 Apr;42(4):513-519. doi: 10.1007/s00270-018-2130-x. Epub 2018 Nov 28.
The aim of this study was to evaluate the efficacy and safety of left gastric artery (LGA) embolization for the treatment of overweight patients who weren't candidates for bariatric surgery.
We retrospectively collected data of 16 patients who underwent a selective embolization of the LGA. The mean body mass index (BMI) before intervention was 28.9 kg/m ± 2.5, and therefore, patients were not candidates for bariatric surgery in Belgium. The embolization was realized with 500-700 µm particles via the right common femoral artery approach. Before and following the intervention, an upper endoscopy was performed. Patient demographics, weight loss, hunger sensation and a satisfactory scale were reviewed.
Between February 2015 and May 2017, 16 overweight patients were treated, one embolization was unsuccessful. Four (25%) patients were lost in follow-up. Nine (56%) patients showed early weight loss, one (6%) maintained his bodyweight and one (6%) patient underwent bariatric surgery 2 years after consultation. Only one (6%) patient had a gastric ulceration on control endoscopy. One (6%) patient ended in the intensive care unit for pancreatitis and gastric perforation. The mean weight loss was 8 kg ± 5.12, reducing their mean BMI to 25.5 ± 3.5. The hunger sensation was decreased, and patients were satisfied.
This is a preliminary study in an overweight population that appears to induce weight loss and appetite suppression. Larger studies are needed to confirm these preliminary findings.
本研究旨在评估左胃动脉（LGA）栓塞术治疗不适合进行减肥手术的超重患者的疗效和安全性。
我们回顾性收集了16例行LGA选择性栓塞术患者的数据。干预前平均体重指数（BMI）为28.9 kg/m²±2.5，因此这些患者不符合比利时减肥手术的标准。通过右股总动脉途径用500 - 700 µm的微粒进行栓塞。干预前后均进行了上消化道内镜检查。对患者的人口统计学资料、体重减轻情况、饥饿感和满意度量表进行了评估。
2015年2月至2017年5月期间，对16例超重患者进行了治疗，1例栓塞失败。4例（25%）患者失访。9例（56%）患者出现早期体重减轻，1例（6%）体重维持不变，1例（6%）患者在咨询后2年接受了减肥手术。仅1例（6%）患者在对照内镜检查时出现胃溃疡。1例（6%）患者因胰腺炎和胃穿孔入住重症监护病房。平均体重减轻8 kg±5.12，平均BMI降至25.5±3.5。饥饿感减轻，患者感到满意。
这是一项针对超重人群的初步研究，似乎能引起体重减轻和食欲抑制。需要更大规模的研究来证实这些初步发现。
