Department of Psychology, University of New Mexico, Albuquerque, New Mexico.
Department of Psychology, University of New Mexico, Albuquerque, New Mexico.
J Pain. 2018 Oct;19(10):1181-1188. doi: 10.1016/j.jpain.2018.04.013. Epub 2018 Jun 4.
Opioid misuse is regularly associated with disrupted functioning in those with chronic pain. Less work has examined whether alcohol misuse may also interfere with functioning. This study examined frequency of opioid and alcohol misuse in 131 individuals (61.1% female) prescribed opioids for the treatment of chronic pain. Participants completed an anonymous survey online, consisting of measures of pain, functioning, and opioid and alcohol misuse. Cut scores were used to categorize individuals according to substance misuse status. Individuals were categorized as follows: 35.9% (n = 47) were not misusing either opioids or alcohol, 22.9% (n = 30) were misusing both opioids and alcohol, 38.2% (n = 50) were misusing opioids alone, and only 3.0% (n = 4) were misusing alcohol alone. A multivariate analysis of variance was performed to examine differences in pain and functioning between groups (after excluding individuals in the alcohol misuse group due to the small sample size). Group comparisons indicated that individuals who were not misusing either substance were less disabled and distressed in comparison to those who were misusing opioids alone or both opioids and alcohol. No differences were indicated between the latter 2 groups. Overall, the observed frequency of opioid misuse was somewhat higher in comparison to previous work (approximately 1 out of every 3 participants), and misuse of both alcohol and opioids was common (approximately 1 out of every 5 participants). While these data are preliminary, they do suggest that issues of substance misuse in those with chronic pain extends beyond opioids alone.
Opioid and alcohol misuse was examined in 131 individuals prescribed opioids for chronic pain. In total, 35.9% were not misusing either, 22.9% were misusing both, 38.2% were misusing opioids, and 3.1% were misusing alcohol. Individuals not misusing either were generally less disabled and distressed compared to those misusing opioids or both.
阿片类药物滥用经常与慢性疼痛患者的功能障碍有关。关于酒精滥用是否也会干扰功能的研究较少。本研究调查了 131 名(61.1%为女性)慢性疼痛患者服用阿片类药物治疗时阿片类药物和酒精滥用的频率。参与者在线完成了一份匿名调查,包括疼痛、功能和阿片类药物和酒精滥用的测量。使用切割分数根据物质滥用状况对个体进行分类。个体分类如下:35.9%(n=47)既没有滥用阿片类药物也没有滥用酒精,22.9%(n=30)同时滥用阿片类药物和酒精,38.2%(n=50)单独滥用阿片类药物,只有 3.0%(n=4)单独滥用酒精。进行了多变量方差分析,以检查组间疼痛和功能的差异(由于酒精滥用组的样本量较小,排除该组个体后)。组间比较表明,与单独滥用阿片类药物或同时滥用阿片类药物和酒精的个体相比,未滥用任何物质的个体功能障碍和痛苦程度较低。后两组之间没有差异。总体而言,与以前的工作相比,阿片类药物滥用的频率略高(大约每 3 名参与者中就有 1 名),同时滥用酒精和阿片类药物很常见(大约每 5 名参与者中就有 1 名)。虽然这些数据是初步的,但它们确实表明慢性疼痛患者的物质滥用问题不仅仅局限于阿片类药物。
本研究调查了 131 名因慢性疼痛而开阿片类药物的患者的阿片类药物和酒精滥用情况。总共有 35.9%的人没有滥用任何药物,22.9%的人同时滥用两种药物,38.2%的人滥用阿片类药物,3.1%的人滥用酒精。与滥用阿片类药物或同时滥用阿片类药物和酒精的个体相比,未滥用任何药物的个体通常功能障碍和痛苦程度较低。