Wong K S, Wong S N, Tham S N, Giam Y C
Middle Road Hospital, Singapore.
Ann Acad Med Singap. 1988 Oct;17(4):520-3.
This study was to investigate the epidermiological, etiological, clinical and prognostic aspects of patients with Generalised Exfoliative Dermatitis in Singapore. From 1981 to 1985, all patients with exfoliative dermatitis or erythroderma admitted to our dermatology wards were included into this study. A standard protocol was filled in for each patient, and they were subsequently followed up at our out-patient clinics. There were 79 male and 29 female patients (sex ratio 2.7:1). The average age was 61.5 years. Most of the patients were from low social income groups. Apart from scaling and erythema, peripherial oedema was the most common finding (44%), followed by hair loss (25%) and lymphadenopathy (22%), 15% of patients had haemoglobin level 10G/dl. The main etiological groups were eczema/dermatitis, psoriasis, drug reactions and those with unknown causes. Two patients were suffering from congenital dermatoses. None of our patients was casually related to malignancy. This study suggested that GED was not a fatal disease among our patients, and they often had a good prognosis.
本研究旨在调查新加坡泛发性剥脱性皮炎患者的流行病学、病因学、临床及预后情况。1981年至1985年期间，所有入住我院皮肤科病房的剥脱性皮炎或红皮病患者均纳入本研究。为每位患者填写一份标准方案，随后在我院门诊进行随访。共有79例男性患者和29例女性患者（性别比为2.7:1）。平均年龄为61.5岁。大多数患者来自社会低收入群体。除了脱屑和红斑外，外周水肿是最常见的表现（44%），其次是脱发（25%）和淋巴结病（22%），15%的患者血红蛋白水平低于10G/dl。主要病因组为湿疹/皮炎、银屑病、药物反应及病因不明者。两名患者患有先天性皮肤病。我们的患者均与恶性肿瘤无因果关系。本研究表明，泛发性剥脱性皮炎在我们的患者中并非致命疾病，且他们通常预后良好。
