Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair, Arkes 1600, Chicago, IL, 60611, USA.
University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Am J Clin Dermatol. 2024 Nov;25(6):927-950. doi: 10.1007/s40257-024-00886-9. Epub 2024 Sep 30.
Erythroderma, an inflammatory skin condition characterized by widespread erythema with variable degrees of exfoliation, pustulation, or vesiculobullous formation, is associated with high morbidity and mortality. Determining the underlying cause of erythroderma frequently presents a diagnostic challenge, which may contribute to the condition's relatively poor prognosis. This review covers the clinical presentation, pathophysiology, diagnosis, and treatment of erythroderma. It discusses similarities and differences among the many underlying etiologies of the condition and differences between erythrodermic and non-erythrodermic presentations of the same dermatosis. Finally, this article explores current research that may provide future tools in the diagnosis and management of erythroderma.
红皮病，一种以广泛红斑伴不同程度脱屑、脓疱或水疱形成为特征的炎症性皮肤疾病，与高发病率和死亡率相关。确定红皮病的根本原因通常具有诊断挑战性，这可能导致该病的预后相对较差。本文综述了红皮病的临床表现、病理生理学、诊断和治疗。文中讨论了该病众多潜在病因之间的相似性和差异性，以及同一皮肤病的红皮病和非红皮病表现之间的差异。最后，本文探讨了当前的研究，这些研究可能为红皮病的诊断和管理提供未来的工具。
