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化妆品中使用的聚醚羊毛脂的安全性评估。

Safety Assessment of Polyether Lanolins as Used in Cosmetics.

作者信息

Becker Lillian C, Bergfeld Wilma F, Belsito Donald V, Hill Ronald A, Klaassen Curtis D, Liebler Daniel C, Marks James G, Shank Ronald C, Slaga Thomas J, Snyder Paul W, Andersen F Alan, Heldreth Bart

机构信息

1 Scientific Analyst/Writer, Cosmetic Ingredient Review, Washington, DC, USA.

2 Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.

出版信息

Int J Toxicol. 2018 May/Jun;37(1_suppl):19S-27S. doi: 10.1177/1091581817740120.

DOI:10.1177/1091581817740120
PMID:29761732
Abstract

The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 39 polyether lanolin ingredients as used in cosmetics. These ingredients function mostly as hair conditioning agents, skin conditioning agent-emollients, and surfactant-emulsifying agents. The Panel reviewed available animal and clinical data, from previous CIR safety assessments of related ingredients and components. The similar structure, properties, functions, and uses of these ingredients enabled grouping them and using the available toxicological data to assess the safety of the entire group. The Panel concluded that these polyether lanolin ingredients are safe in the practices of use and concentration as given in this safety assessment.

摘要

化妆品成分审查(CIR)专家小组评估了化妆品中使用的39种聚醚羊毛脂成分的安全性。这些成分主要起头发调理剂、皮肤调理剂-润肤剂和表面活性剂-乳化剂的作用。专家小组审查了现有的动物和临床数据,以及之前CIR对相关成分和组分的安全性评估数据。这些成分相似的结构、性质、功能和用途使得可以将它们分组,并利用现有的毒理学数据来评估整个组的安全性。专家小组得出结论,在本安全性评估给出的使用方法和浓度下,这些聚醚羊毛脂成分是安全的。

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