Yang Liu, Zhao Yinghu, Wang Fang, Liu Haiying, Li Qinqin, Wang Linbian, Gao Li
School of Chemical Engineering and Technology, North University of China, Taiyuan 030051, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2017 Dec 1;34(6):972-976. doi: 10.7507/1001-5515.201701038.
Melanin nanoparticles (MNPs) not only retain the inherent characteristics of melanin (metal ion chelation, photothermal conversion property, .), but also can exhibit more excellent properties, such as high dispersion stability, good biocompatibility and biodegradability, . Furthermore, these performances can be enhanced to target the specific sites and treat diseases by the surface modification or combination with functional substance. In this paper, the characteristics, preparation methods and applications of MNPs were reviewed. It provides a reference for further development of application for MNPs, and theoretical basis for practice in biology, medicine and so on.
黑色素纳米颗粒(MNPs)不仅保留了黑色素的固有特性(金属离子螯合、光热转换特性等),而且还能展现出更优异的性能,如高分散稳定性、良好的生物相容性和生物降解性等。此外,通过表面修饰或与功能物质结合,这些性能可以得到增强,以靶向特定部位并治疗疾病。本文综述了MNPs的特性、制备方法及应用。它为MNPs应用的进一步发展提供了参考,也为生物学、医学等领域的实践提供了理论依据。