Faculty of Education and Health Sciences, School of Allied Health, University of Limerick, Limerick, Ireland.
Faculty of Education and Health Sciences, Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.
Scand J Med Sci Sports. 2018 Sep;28(9):1960-1969. doi: 10.1111/sms.13214. Epub 2018 May 30.
To quantify physical activity (PA) levels in people with multiple sclerosis (pwMS) using objective measurement and to establish using a meta-analytical approach if pwMS are less active than the general population. A systematic search of eight databases was conducted. Cohort and intervention studies which included an objective measure of PA were included. Objective PA outputs of steps per day and minutes of moderate-vigorous activity (MVPA) per day were extracted from the MS studies and the published NHANES dataset. Meta-analysis was used to compare the differences between the groups for these parametric outcomes. A general population sample from the National Health and Nutritional Examination Survey (NHANES) in the United States of America was used as a comparative group. The systematic search resulted in 32 papers (n = 2 randomized control trials, n = 30 cohort studies). A total of 3 762 pwMS were included. The sample was largely female (n = 3 118, 82.8%) and ambulatory with/without use of an aid (n = 31 studies). There were significant differences between the MS and the published NHANES comparative group with respect to 1) steps per day [mean difference: -3845 (-4120.17, -3569.83), P < .0001, n = 10 studies] and 2) minutes of MVPA per day [mean difference: 9.00 (-12.5, -5.4), P < .0001, n = 3 studies], indicating pwMS are less physically active than the NHANES sample. Results suggest that pwMS are less physically active than a general population across PA outputs of steps per day and minutes of MVPA per day. There is a need to increase PA levels among pwMS.
使用客观测量方法量化多发性硬化症患者（pwMS）的身体活动（PA）水平，并通过荟萃分析方法确定 pwMS 是否比一般人群活动量更少。方法：系统检索了 8 个数据库。纳入包含 PA 客观测量的队列研究和干预研究。从 MS 研究和已发表的 NHANES 数据集提取每天的步数和中等至剧烈活动（MVPA）分钟数等客观 PA 输出。使用荟萃分析比较这些参数结果的组间差异。美国国家健康和营养检查调查（NHANES）中的一般人群样本作为比较组。结果：系统检索共产生 32 篇论文（n=2 项随机对照试验，n=30 项队列研究）。共纳入 3762 名 pwMS。样本主要为女性（n=3118，82.8%），使用或不使用辅助工具进行活动（n=31 项研究）。MS 与已发表的 NHANES 比较组在以下方面存在显著差异：1）每天的步数[平均差异：-3845（-4120.17，-3569.83），P<0.0001，n=10 项研究]和 2）每天 MVPA 分钟数[平均差异：9.00（-12.5，-5.4），P<0.0001，n=3 项研究]，表明 pwMS 的身体活动量比 NHANES 样本少。结论：pwMS 在每天的步数和 MVPA 分钟数等 PA 输出方面比一般人群的身体活动量少。需要增加 pwMS 的身体活动水平。
