Pierrez J, Guerci A, Guerci O
Laboratoire de Cytométrie en Flux, Service de Médecine A, CHU Brabois, Vandaeuvre-les-Nancy.
C R Seances Soc Biol Fil. 1988;182(3):280-5.
The coordination of flux cytometry and of a techniques of leukoconcentration allowed to determine the cellular cycle of nucleated cells of circulating blood, without logs nor enrichment of cellular type on a definitive moment. The study of acute leukemias allow to conclude that: 1) it exists in peripheral blood a synthetic activity of ADN bound to the presence of leukemic or blastic cells; 2) this activity allows to appreciate the spontaneous variations of synthesis and the incidence of chemotherapy.
流式细胞术与白细胞浓缩技术的协同作用，使得在不进行对数分析或在某个特定时刻对细胞类型进行富集的情况下，能够确定循环血液中有核细胞的细胞周期。对急性白血病的研究可以得出以下结论：1）外周血中存在与白血病细胞或原始细胞的存在相关的DNA合成活性；2）这种活性有助于了解合成的自发变化以及化疗的发生率。
