Veselovskaya N N, Zherebko I B
Fiziol Zh (1994). 2016;62(6):118-121. doi: 10.15407/fz62.06.118.
Conducted a comparative analysis of functional changes in tear production in patients with dry eye syndrome and endocrine ophthalmopathy in the conditions of the long-term acting of preservative free medications based on natural substances. A total of 30 people, aged 35 to 53 years old with clinical manifestations of DES on the background of EO were divided on two groups. In I group eye drops of ectoine and in II - artificial tears were administered. The examination included general and specific methods. The term of follow up - 30 days. It was found that long-term use of preservative free eye drops based on ectoine leads to more expressive positive changes in the condition of the anterior surface of the eye and the secretion and quality of the tear.
对干眼症和内分泌性眼病患者在基于天然物质的无防腐剂药物长期作用情况下泪液分泌功能变化进行了对比分析。共有30名年龄在35至53岁之间、以内分泌性眼病为背景且有干眼症临床表现的患者被分为两组。第一组使用依克多因滴眼液，第二组使用人工泪液。检查包括一般方法和特殊方法。随访期为30天。结果发现，长期使用基于依克多因的无防腐剂滴眼液会使眼表状况以及泪液分泌和质量产生更明显的积极变化。
