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采用病灶内注射曲安奈德和加压包扎治疗淋巴管内组织细胞增多症。

Intralymphatic histiocytosis treated with intralesional triamcinolone acetonide and pressure bandage.

作者信息

Soh Jonathan M, Scott Glynis A, Hirokawa Theodore I, Dolohanty Lindsey B

机构信息

Department of Dermatology, University of Rochester School of Medicine and Dentistry, New York, USA.

Department of Dermatology, Department of Pathology, University of Rochester School of Medicine and Dentistry, New York, USA.

出版信息

Cutis. 2018 Apr;101(4):E1-E4.

PMID:29763489
Abstract

Intralymphatic histiocytosis is a rare disorder associated with a variety of inflammatory conditions. We report the case of an 89-year-old woman with a history of a right knee replacement and a ruptured popliteal cyst who developed an erythematous indurated plaque over the surgical scar. Histopathology revealed fibrosis, chronic inflammation, and histiocytes within the lymphatics consistent with intralymphatic histiocytosis. The plaque flattened following intralesional injection of triamcinolone acetonide 10 mg/cc×1.6 cc once monthly for 2 consecutive months and application of a pressure bandage, with no recurrence after 4 months. This treatment may be useful for recalcitrant disease.

摘要

淋巴管内组织细胞增多症是一种与多种炎症性疾病相关的罕见病症。我们报告了一例89岁女性病例,该患者有右膝置换手术史及腘窝囊肿破裂史,其手术瘢痕处出现了一个红斑性硬结斑块。组织病理学检查显示有纤维化、慢性炎症以及淋巴管内的组织细胞,符合淋巴管内组织细胞增多症。经连续两个月每月一次病灶内注射10mg/cc×1.6cc曲安奈德并应用压力绷带后,斑块变平,4个月后未复发。这种治疗方法可能对难治性疾病有用。

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