Chatierjee A, Bajaj A K, Gupta S C
Department of Dermatology and Pathology, M.L.N. Medical College, Allahabad 211001, Uttar Pradesh, India.
Natl Med J India. 1991 May-Jun;4(3):113-115.
Bindis, which Indian women apply on their foreheads, occasionally depigment the skin.
We analysed the adhesive on bindi samples using thin layer chromatography, infrared spectrophotometry, high performance liquid chromatography and patch tested 15 patients with bindi depigmentation, 10 normal individuals and 14 patients with vitiligo.
The bindi adhesive contained about 80% paratertiary butyl phenol-a depigmenting agent with a marked irritant action. Hypersensitivity to the agent did not occur.
Para-tertiary butyl phenol causes depigmentation after bindi application on the forehead and we suggest that the use of this agent as an adhesive be banned.
印度女性点涂在前额的吉祥痣偶尔会导致皮肤色素脱失。
我们采用薄层色谱法、红外分光光度法、高效液相色谱法分析了吉祥痣样本上的黏合剂，并对15例吉祥痣色素脱失患者、10名正常个体及14例白癜风患者进行了斑贴试验。
吉祥痣黏合剂中约含80%的对叔丁基苯酚——一种具有明显刺激作用的色素脱失剂。未出现对该制剂的超敏反应。
对叔丁基苯酚在前额涂抹吉祥痣后会导致色素脱失，我们建议禁止将该制剂用作黏合剂。
