Bajaj A K, Gupta S C, Chatterjee A K
Department of Dermatology and Pathology, MLN Medical College, Uttar Pradesh, India.
Contact Dermatitis. 1990 Feb;22(2):99-102. doi: 10.1111/j.1600-0536.1990.tb01525.x.
100 consecutive cases of contact depigmentation due to bindi during a period of 11 months were studied. Bindi adhesive material was found to contain 80% para-tertiary-butylphenol (PTBP), by thin-layer chromatography, infrared spectrophotometry and high-pressure liquid chromatography. The possibility of hypersensitivity to PTBP was ruled out as none of the 15 patients tested with 2% PTBP and 1% para-tertiary-butylphenol-formaldehyde resin gave any positive reactions. Development of depigmentation could have been due either to individual susceptibility or to constant use for a prolonged period. The area of contact being very small, generalised vitiligo as a result of systemic absorption appeared to be a remote possibility.
在11个月的时间里，对100例连续发生的因佩戴眉心贴导致接触性色素脱失的病例进行了研究。通过薄层色谱法、红外分光光度法和高压液相色谱法发现，眉心贴的粘合材料含有80%的对叔丁基苯酚（PTBP）。对15名使用2% PTBP和1%对叔丁基苯酚 - 甲醛树脂进行测试的患者均未出现任何阳性反应，因此排除了对PTBP过敏的可能性。色素脱失的发生可能是由于个体易感性或长期持续使用。由于接触面积非常小，因全身吸收导致泛发性白癜风的可能性似乎很小。
