Eiben Paola, Rodriguez-Villar Sancho
Department of Critical Care Medicine, King's College Hospital NHS Foundation Trust, SE5 9RS London, UK.
J Surg Case Rep. 2018 Apr 30;2018(4):rjy083. doi: 10.1093/jscr/rjy083. eCollection 2018 Apr.
Periorbital necrotizing fasciitis (PNF) is a severe suppurative infection of the subcutaneous tissue and underlying fascia of the periorbital region. Typically, the course of PNF is milder and has a better prognosis than that of necrotizing fasciitis in other parts of the body. As such, this disease is thought to be associated with a significantly smaller risk of morbidity and mortality. Nevertheless, it is a rare and devastating condition that can lead to disfigurement, blindness and death. Early recognition is critical to improved patient outcomes. Here, we describe a case of PNF in a 60-year-old male that rapidly progressed to widespread systemic involvement and severe multiorgan failure requiring ventilatory, cardiovascular and renal support. Treatment included broad-spectrum antibiotics, intravenous immunoglobulin and surgical debridement. This case highlights the life-threatening nature of PNF, as demonstrated by rapid progression to multiorgan dysfunction and the need of an urgent surgical intervention.
眶周坏死性筋膜炎（PNF）是一种眶周区域皮下组织和深层筋膜的严重化脓性感染。通常，PNF的病程比身体其他部位的坏死性筋膜炎更轻，预后更好。因此，这种疾病被认为发病和死亡风险显著更小。然而，它是一种罕见且具有破坏性的疾病，可导致毁容、失明和死亡。早期识别对于改善患者预后至关重要。在此，我们描述一例60岁男性的PNF病例，该病例迅速进展为广泛的全身受累和严重的多器官功能衰竭，需要通气、心血管和肾脏支持。治疗包括广谱抗生素、静脉注射免疫球蛋白和手术清创。该病例突出了PNF危及生命的性质，表现为迅速进展为多器官功能障碍以及迫切需要进行手术干预。
