Wan Yantong, Jiang Xiaoqin, Lin Xuemei
Department of Anesthesiology, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, People's Republic of China.
Medicine (Baltimore). 2018 May;97(20):e10454. doi: 10.1097/MD.0000000000010454.
Wilson's disease (WD), or hepatolenticular degeneration, is an autosomal recessive disorder with a prevalence of 1:50,000 to 1:100,000 live births.
A 26-year-old primipara with WD was admitted to our hospital, due to awaiting delivery. Her main symptoms were slightly higher total bile acid (TBA) and bilateral depressed edema of lower limbs.
She was at 38 weeks and 4 days of gestation with a 15-year history of WD, controlled with penicillamine in the past and replaced by zinc preparations from three months before pregnancy.
General anesthesia was successfully administered for a female with WD undergoing cesarean delivery.
General anesthesia can be administered in an asymptomatic primigravida with WD. Appropriate anesthetics choice can effectively minimize the rates of complications and sequelae.
威尔逊病（WD），即肝豆状核变性，是一种常染色体隐性疾病，活产患病率为1:50,000至1:100,000。
一名26岁患有WD的初产妇因待产入院。她的主要症状是总胆汁酸（TBA）略高和双下肢凹陷性水肿。
她妊娠38周零4天，有15年WD病史，过去用青霉胺控制，妊娠前三个月改用锌制剂。
一名患有WD的女性剖宫产手术中全身麻醉成功实施。
全身麻醉可用于无症状的WD初产妇。选择合适的麻醉剂可有效降低并发症和后遗症的发生率。
