Lee L, Saboui M, Mersereau T
Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.
Can Commun Dis Rep. 2015 Feb 20;41(Suppl 1):9-10. doi: 10.14745/ccdr.v41is1a02.
To provide a summary of the weekly report on influenza activity in Canada for the week of February 8-14, 2015.
The programs consists of a network of sentinel laboratories, sentinel primary care practices, provincial and territorial ministries of health, and sentinel hospitals that report on the seven main influenza indictors on a weekly basis across Canada. Information is aggregated by the program and disseminated through weekly reports during the activity influenza season and bi-weekly reports during the low season.
In week 6, influenza activity levels declined for six surveillance indicators. Seven regions reported widespread activity: Ontario (2), Quebec (2), Manitoba (1), Prince Edward Island (1) and Newfoundland (1). Twenty-one regions reported localized activity: New Brunswick (7), Nova Scotia (5), Ontario (5), Alberta (1) and Manitoba (1), and 22 regions reported sporadic activity. The national influenza-like-illness (ILI) consultation rate decreased from the previous week to 44.5 consultations per 1,000, which is higher than expected levels for week 6. A total of 74 outbreaks have been reported this week and the majority of outbreaks this season have been reported in long-term care facilities (LTCF). Laboratory detections of influenza decreased from the previous week from 1,884 in week 5 to 1,625 in week 6. The number of positive respiratory syncytial virus (RSV) tests decreased to 914 RSV detections down from 1,110 RSV detections in week 5 and remains the second most frequently detected virus after influenza. To date, 4,817 influenza hospitalizations and 342 deaths have been reported through the national severe outcome surveillance system; with the majority reported in adults aged 65 and over. In the 2014-15 season, the National Microbiology Laboratory (NML) has characterized 194 influenza viruses and found that the majority of influenza A (H3N2) specimens tested to date was not optimally matched to the vaccine strain; but all those tested for resistance were all found to be sensitive to oseltamivir and zanamivir. Two Canadian studies, one by the Sentinel Physician Surveillance Network (SPSN) and the other by the Canadian Immunization Research Network (CIRN), examined mid-season data on the current influenza vaccine's effectiveness and both studies observed little to no vaccine protection against the A(H3N2) virus. (See ID News).
Influenza A (H3N2) continues to be the most common type of influenza affecting Canadians. In laboratory detections, hospitalizations and deaths, the majority of cases have been among seniors greater than 65 years of age. The patterns of many indicators such as laboratory detections and outbreaks have been similar to the 2012-13 season when influenza A (H3N2) also predominated. The NML and the SPSN study have found that the majority of the circulating influenza A (H3N2) specimens are not optimally matched to the vaccine strain. Several indicators have been continuously declining since week 1, indicating that the peak of the 2014-15 influenza season has passed. The surveillance system will continue to monitor influenza activity throughout the remainder of the 2014-15 season and publish findings in the report.
总结2015年2月8日至14日当周加拿大流感活动周报。
该项目由一个监测实验室网络、基层医疗监测点、省和地区卫生部门以及监测医院组成,这些机构每周汇报加拿大境内七个主要流感指标。项目对信息进行汇总,并在流感活动季期间通过周报发布,在非活动季期间每两周发布一次报告。
在第6周,六个监测指标的流感活动水平下降。七个地区报告有广泛传播:安大略省(2个)、魁北克省(2个)、马尼托巴省(1个)、爱德华王子岛省(1个)和纽芬兰省(1个)。21个地区报告有局部传播:新不伦瑞克省(7个)、新斯科舍省(5个)、安大略省(5个)、艾伯塔省(1个)和马尼托巴省(1个),22个地区报告有散发病例。全国流感样疾病(ILI)咨询率较前一周下降至每1000人中有44.5次咨询,高于第6周的预期水平。本周共报告了74起疫情,本季大多数疫情报告发生在长期护理机构(LTCF)。流感实验室检测较前一周有所下降,从第5周的1884例降至第6周的1625例。呼吸道合胞病毒(RSV)阳性检测数量降至914例,低于第5周的1110例,仍然是仅次于流感的第二常见检测病毒。截至目前,通过国家严重后果监测系统已报告48,17例流感住院病例和342例死亡病例;大多数报告病例为65岁及以上成年人。在2014 - 15季,国家微生物实验室(NML)已对194株流感病毒进行了分型,发现到目前为止检测的大多数甲型(H3N2)流感病毒株与疫苗株的匹配度不理想;但所有检测其耐药性的病毒均对奥司他韦和扎那米韦敏感。两项加拿大研究,一项由监测医生监测网络(SPSN)开展,另一项由加拿大免疫研究网络(CIRN)开展,对当前流感疫苗有效性的季中数据进行了研究,两项研究均观察到该疫苗对甲型(H3N2)病毒几乎没有保护作用。(见ID新闻)
甲型(H3N2)流感仍然是影响加拿大人的最常见流感类型。在实验室检测、住院病例和死亡病例中,大多数病例为65岁以上老年人。许多指标的模式,如实验室检测和疫情,与2012 - 13季相似,当时也是甲型(H3N2)流感占主导。NML和SPSN的研究发现,大多数传播的甲型(H3N2)流感病毒株与疫苗株的匹配度不理想。自第1周以来,几个指标持续下降,表明2014 - 15流感季的高峰期已经过去。监测系统将在2014 - 15季剩余时间继续监测流感活动,并在报告中发布结果。