Wilson W B, Smith D B, Wright R R, Seibert C E
Department of Ophthalmology, University of Colorado School of Medicine, Denver.
J Clin Neuroophthalmol. 1988 Dec;8(4):255-61.
A 51-year-old woman with Sneddon's disease presented with transient right hemifield loss of vision and transient right-sided weakness. Over the preceding decade she had experienced a slow decline in mental function. She also had hypertension, migraine, and a mixed seizure disorder. She had skin changes typical for generalized livedo reticularis but she did not have Raynaud's phenomenon or winter ulcerations. Her disease was not understood until the stroke-related symptoms were associated with the skin abnormalities. We review the neuro-ophthalmic manifestations of Sneddon's disease and add data from our case to the growing body of fact that suggests that Sneddon's disease may be an immunologically mediated vasculopathy.
一名患有斯内登氏病的51岁女性出现短暂性右半视野视力丧失和短暂性右侧肢体无力。在过去十年中，她的 mental function 缓慢下降。她还患有高血压、偏头痛和混合型癫痫症。她有全身性网状青斑的典型皮肤变化，但没有雷诺现象或冬季溃疡。直到与中风相关的症状与皮肤异常相关联，她的病情才得以明确。我们回顾了斯内登氏病的神经眼科表现，并将我们病例的数据添加到越来越多的事实中，这些事实表明斯内登氏病可能是一种免疫介导的血管病。
