Beta-endorphin-like immunoreactivity increases in cerebrospinal fluid of acute head-injured patients.

作者信息

Yao J J, Cheng Z, Ce C C, Hai W C, Xiang Z Y, Cheng L B

机构信息

Department of Neurosurgery, Chang Zheng Hospital, Second Military Medical College, Shanghai, People's Republic of China.

出版信息

Neuropeptides. 1988 Oct;12(3):177-9. doi: 10.1016/0143-4179(88)90051-0.

beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, and severe cerebral contusion patients were 51.9 +/- 5.6 pg/ml, 110.5 +/- 14.5 pg/ml, and 173.8 +/- 20.1 pg/ml respectively, with significant difference between them. The results also showed that beta-ELI may reflect the prognosis of acute head-injured patients.