Clark James M, Hopkins Michael P, Krol Emilia, Chase Daniel, Sparks Dorothy
Conn Med. 2017 Mar;81(3):165-167.
In recentyears, theincidence ofvul- var carcinoma has increased over 400%, specifically in the population of young women. We present a patient with an extensive history of recurrent vulvar carcinoma in situ who underwent multiple surgi- cal procedures and subsequent reconstruction with a skin graft, who then returned with a rare recur- rence in the graft. Multiple hypotheses have been proposedto explain the recurrence ofthis type ofcar- cinoma; however, none provides a solid explanation. It has been noted that the increase in the incidence of vulvar cancer correlates with the increased incidence of HPV infection; the relationship between the two has been well-established. In conclusion, we recommend close and long-term follow-up for high-risk patients with this type of neoplasm.
近年来，外阴癌的发病率增长超过了400%，在年轻女性群体中尤为明显。我们报告了一名有广泛复发性原位外阴癌病史的患者，该患者接受了多次手术及随后的皮肤移植重建手术，之后移植部位出现罕见复发。人们提出了多种假说来解释这类癌症的复发；然而，没有一种能给出确凿的解释。已经注意到外阴癌发病率的增加与HPV感染率的上升相关；两者之间的关系已得到充分证实。总之，我们建议对这类肿瘤的高危患者进行密切的长期随访。
