MRC Centre for Regenerative Medicine, University of Edinburgh, Little France Drive, Edinburgh EH16 4UU, UK.
Neuron. 2018 May 16;98(4):684-686. doi: 10.1016/j.neuron.2018.05.005.
Live imaging studies in mice show that adult-born oligodendrocytes and myelin are remarkably stable. Neural activity enhances oligodendrocyte integration, arguing that internode addition rather than alteration represents the mechanism for any experience-dependent cortical myelination changes that might underpin learning.
在小鼠中的活体成像研究表明,成年产生的少突胶质细胞和髓鞘具有惊人的稳定性。神经活动增强了少突胶质细胞的整合,这表明增加神经节段而不是改变它们代表了任何与经验相关的皮层髓鞘变化的机制,这些变化可能是学习的基础。