时间感知的神经基础：不同功能的分布式机制。
The Neural Basis of Timing: Distributed Mechanisms for Diverse Functions.
机构信息
Champalimaud Research, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Departments of Neurobiology and Psychology and Brain Research Institute, Integrative Center for Learning and Memory, University of California, Los Angeles, Los Angeles, CA, USA.
出版信息
Neuron. 2018 May 16;98(4):687-705. doi: 10.1016/j.neuron.2018.03.045.
Timing is critical to most forms of learning, behavior, and sensory-motor processing. Converging evidence supports the notion that, precisely because of its importance across a wide range of brain functions, timing relies on intrinsic and general properties of neurons and neural circuits; that is, the brain uses its natural cellular and network dynamics to solve a diversity of temporal computations. Many circuits have been shown to encode elapsed time in dynamically changing patterns of neural activity-so-called population clocks. But temporal processing encompasses a wide range of different computations, and just as there are different circuits and mechanisms underlying computations about space, there are a multitude of circuits and mechanisms underlying the ability to tell time and generate temporal patterns.
时间对于大多数形式的学习、行为和感觉运动处理都至关重要。越来越多的证据支持这样一种观点，即由于时间在广泛的大脑功能中都非常重要，因此时间依赖于神经元和神经回路的内在和普遍特性；也就是说，大脑利用其天然的细胞和网络动力学来解决各种时间计算问题。许多回路已经被证明可以在不断变化的神经活动模式中编码经过的时间，即所谓的群体时钟。但是，时间处理涵盖了广泛的不同计算，就像空间计算有不同的回路和机制一样，时间计算的能力和产生时间模式也有许多回路和机制。
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