Madzhunov N, Niakolov K
Probl Khig. 1988;13:182-8.
Immunological and functional studies are performed on workers engaged in the production of plastics, artificial fibres and dyes, in view of clarifying some mechanisms in the evolution of the contact dermatitis and the related with it early changes. The study establishes increased values of IgA and IgG in workers in contact with irritating substances and increased values of IgG in workers in contact with sensitizing substances. In the latter is registered a decrease in the active and the total rosettes. The functional investigations, performed on 292 workers point out to no essential deviations in pH values in the limits of the physiological variability. The alkaline resistance of the skin is decreased in 51% of the examined, who are in contact with irritating substances and in 29.7% exposed mainly to sensitizing substances.
针对从事塑料、人造纤维和染料生产的工人开展了免疫学和功能研究，旨在阐明接触性皮炎演变过程中的一些机制以及与之相关的早期变化。研究发现，接触刺激性物质的工人中IgA和IgG值升高，接触致敏性物质的工人中IgG值升高。在接触致敏性物质的工人中，活性玫瑰花结和总玫瑰花结数量减少。对292名工人进行的功能研究表明，在生理变异范围内，pH值无显著偏差。在接触刺激性物质的受检者中，51%的人皮肤耐碱性降低；在主要接触致敏性物质的受检者中，29.7%的人皮肤耐碱性降低。
