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极端嗜盐多形古菌病毒HRPV9扩展了具有整合酶的嗜盐脂病毒的多样性。

Extremely halophilic pleomorphic archaeal virus HRPV9 extends the diversity of pleolipoviruses with integrases.

作者信息

Atanasova Nina S, Demina Tatiana A, Krishnam Rajan Shanthi Sudar N V, Oksanen Hanna M, Bamford Dennis H

机构信息

Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland; Finnish Meteorological Institute, Erik Palménin aukio 1, FI-00560, Helsinki, Finland.

Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland.

出版信息

Res Microbiol. 2018 Nov;169(9):500-504. doi: 10.1016/j.resmic.2018.04.004. Epub 2018 May 14.

Abstract

Certain pleomorphic archaeal viruses are highly infectious even at saturated salt. These viruses belong to the genus Betapleolipovirus of the recently described archaeal virus family Pleolipoviridae. Pleolipoviruses comprise single-stranded or double-stranded, circular or linear DNA genomes that share countless homologues among various archaeal genetic elements. Here we describe a new extremely halophilic betapleolipovirus, Halorubrum pleomorphic virus 9 (HRPV9), which has an integrase gene. We also identified new genes encoding minor pleolipoviral structural proteins. The studies on HRPV9 enhance our knowledge on pleolipoviruses, especially their reciprocal relatedness and relation to certain archaeal plasmids, proviruses and membrane vesicles.

摘要

某些多形古菌病毒即使在饱和盐环境下仍具有高度传染性。这些病毒属于最近描述的古菌病毒科嗜盐脂病毒科中的嗜盐脂病毒属。嗜盐脂病毒包含单链或双链、环状或线性DNA基因组,这些基因组在各种古菌遗传元件之间共享无数同源物。在此,我们描述了一种新的极端嗜盐嗜盐脂病毒——嗜盐栖嗜盐古菌多形病毒9(HRPV9),它具有一个整合酶基因。我们还鉴定出了编码嗜盐脂病毒次要结构蛋白的新基因。对HRPV9的研究增进了我们对嗜盐脂病毒的了解,尤其是它们之间的相互关系以及与某些古菌质粒、前病毒和膜泡的关系。

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