Ankara Education and Research Hospital, Department of Cardiology, Ankara 06230, Turkey.
Private Yenisehir Hospital, Department of Cardiology, Mersin, Turkey.
Cardiovasc Pathol. 2018 Jul-Aug;35:37-47. doi: 10.1016/j.carpath.2018.04.005. Epub 2018 Apr 16.
Coronary artery ectasia describes a local or diffuse dilatation of the epicardial coronary arteries. This review summarizes the molecular and cellular mechanisms involved in the pathogenesis of coronary artery ectasia. Better identification of the pathophysiologic steps will shed light into the clinical significance and may have direct implications for the management strategies of this disease. Additionally, understanding the underlying etiology may help to improve treatment modalities specific to coronary artery ectasia.
冠状动脉扩张是指心外膜冠状动脉的局部或弥漫性扩张。本文综述了冠状动脉扩张发病机制中的分子和细胞机制。更好地识别病理生理步骤将阐明其临床意义，并可能对该疾病的治疗策略直接产生影响。此外，了解潜在病因可能有助于改善针对冠状动脉扩张的特定治疗方式。
