Waly H M, Elayda M A, Lee V V, el-Said G, Reul G J, Hall R J
Department of Adult Cardiology, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
Tex Heart Inst J. 1997;24(4):349-52.
We conducted a retrospective study of 45 Egyptian patients with coronary artery ectasia who underwent coronary bypass grafting at our institution between 1980 and 1995. We examined the anatomic distribution and type of coronary ectasia and its association with coronary risk factors in these patients, and evaluated the severity of their coronary artery disease. We compared these findings with those from a group of 230 Egyptian patients who did not have coronary ectasia. These patients also underwent coronary artery bypass grafting between 1980 and 1995 at our institution. Obesity was present in 60% of the patients who had coronary artery ectasia, compared with 42% of patients who did not have ectasia (P < 0.01). Coronary artery ectasia was not related to any coronary risk factors other than obesity. However, patients who had ectasia did have a higher rate of triple-vessel coronary artery disease than did patients without ectasia (82% vs 67%, P < 0.05). Of the coronary vessels affected by ectasia, 43% were left anterior descending arteries. Diffuse disease was noted in 84% of all ectatic segments. We conclude that in this patient population, 2 conditions had a positive correlation with coronary ectasia: obesity and the severity of coronary artery disease.
我们对1980年至1995年间在我院接受冠状动脉旁路移植术的45例埃及冠状动脉扩张患者进行了一项回顾性研究。我们检查了这些患者冠状动脉扩张的解剖分布、类型及其与冠状动脉危险因素的关联,并评估了他们冠状动脉疾病的严重程度。我们将这些结果与一组230例无冠状动脉扩张的埃及患者的结果进行了比较。这些患者也于1980年至1995年间在我院接受了冠状动脉旁路移植术。60%有冠状动脉扩张的患者存在肥胖,而无扩张的患者中这一比例为42%(P<0.01)。除肥胖外,冠状动脉扩张与任何冠状动脉危险因素均无关联。然而,有扩张的患者三支血管冠状动脉疾病的发生率高于无扩张的患者(82%对67%,P<0.05)。在受扩张影响的冠状动脉血管中,43%为左前降支动脉。在所有扩张节段中,84%发现有弥漫性病变。我们得出结论,在这一患者群体中,有两种情况与冠状动脉扩张呈正相关:肥胖和冠状动脉疾病的严重程度。