Sakarya University, Engineering Faculty, Department of Metallurgy and Materials Engineering, Thermal Spray Research and Development Laboratory, 54187, Esentepe, Sakarya, Turkey; Institute of Biomaterials, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany.
Institute of Biomaterials, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany.
Colloids Surf B Biointerfaces. 2018 Sep 1;169:176-182. doi: 10.1016/j.colsurfb.2018.05.005. Epub 2018 May 3.
This study focuses on the optimization of electrophoretic deposition (EPD) and suspension parameters for producing PEEK-hydroxyapatite (HA) coatings with feasible microstructure, adhesion strength, and in-vitro bioactivity. Nanostructured hydroxyapatite (HA) micro-granules were incorporated with PEEK to form PEEK-hydroxyapatite composite coatings via EPD. After EPD, a heat-treatment at 375 °C was applied for densification of the coatings and for enhancing the adhesion between the coatings and the substrates. It was found that both adhesion strength and in-vitro bioactivity of the coatings were dependent on the PEEK and HA relative contents. Thus, increasing the amount of HA improved the bioactivity while decreased the adhesion strength of the coatings. Apatite-like layer formation was observed on coatings with high HA content after incubation for three days in simulated body fluid (SBF). Finally, a deposition mechanism was proposed for the EPD of the PEEK-hydroxyapatite composite system.
本研究专注于通过电泳沉积（EPD）和悬浮参数的优化，制备具有可行微观结构、附着强度和体外生物活性的 PEEK-羟基磷灰石（HA）涂层。通过 EPD 将纳米结构的羟基磷灰石（HA）微颗粒与 PEEK 结合，形成 PEEK-羟基磷灰石复合涂层。EPD 后，在 375°C 下进行热处理，以对涂层进行致密化，并增强涂层与基底之间的附着。结果表明，涂层的附着强度和体外生物活性都取决于 PEEK 和 HA 的相对含量。因此，增加 HA 的量可以提高生物活性，但会降低涂层的附着强度。在模拟体液（SBF）中孵育三天后，发现高 HA 含量的涂层上形成了类磷灰石层。最后，提出了 EPD 制备 PEEK-羟基磷灰石复合体系的沉积机理。
