Baumgarten Lee, Dabaja Ali A
Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI, 48202, USA.
Curr Urol Rep. 2018 May 17;19(7):46. doi: 10.1007/s11934-018-0796-x.
Our aim is to review the steps of diagnosis and management of gynecomastia with a special focus on treatment of gynecomastia associated with androgen deprivation therapy for prostate cancer.
Recent studies investigating tamoxifen and radiation therapy for both therapy and prophylaxis of bicalutamide-induced gynecomastia are reviewed. Gynecomastia is a common clinical problem, affecting between one and two thirds of middle-aged men. Diagnosis is typically made by history and physical exam. Common causes include chronic medical conditions and medications; however, unexplained gynecomastia should prompt laboratory work-up, followed by appropriate imaging studies to evaluate for hormone producing cancers. For patients taking bicalutamide for treatment of prostate cancer, tamoxifen or radiation therapy for gynecomastia are excellent options.
我们的目的是回顾男性乳房发育症的诊断和管理步骤，特别关注与前列腺癌雄激素剥夺治疗相关的男性乳房发育症的治疗。
综述了近期关于他莫昔芬和放射治疗用于比卡鲁胺所致男性乳房发育症的治疗和预防的研究。男性乳房发育症是一个常见的临床问题，影响三分之一至三分之二的中年男性。诊断通常通过病史和体格检查做出。常见原因包括慢性疾病和药物；然而，不明原因的男性乳房发育症应促使进行实验室检查，随后进行适当的影像学检查以评估是否存在激素产生性癌症。对于接受比卡鲁胺治疗前列腺癌的患者，他莫昔芬或放射治疗是治疗男性乳房发育症的极佳选择。
