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斯坦尼斯瓦夫·切哈诺夫斯基(1869 - 1945)的遗产——前列腺增生发病机制的发现者——以非凡的标志闪耀着神奇的光芒。

Heritage of Stanislaw Ciechanowski (1869-1945)-Discoverer of pathogenesis of prostatic hyperplasia-passionis insignia signis fulgent mirificis .

作者信息

Wincewicz Andrzej, Woltanowski Piotr, Sulkowski Stanisław

机构信息

Specialist Medical Practice-Pathologist, Non Public Health Care Unit, Department of Pathology (NZOZ Zakład Patologii Spółka z o.o.), Kielce, Poland.

Board Member and General Secretary of Information and Organization Centre for the Research on the Public Finances and Tax Law in the Countries of Central and Eastern Europe, Faculty of Law, Department of Law of Public Finances, University of Bialystok, Bialystok, Poland.

出版信息

Prostate. 2018 Sep;78(12):938-948. doi: 10.1002/pros.23652. Epub 2018 May 18.

DOI:10.1002/pros.23652
PMID:29774590
Abstract

BACKGROUND

Prostatic enlargement was first correctly recognized as a prostatic hyperplasia by professor of anatomic pathology, Stanisław Ciechanowski (1869-1945) in Cracow on contrary to Parisian urologist Jean Casimir Félix Guyon's concepts of progressing atherosclerosis as a morphological cause of prostatic overgrowth and mechanical insufficiency of lower urinary tract.

METHODS

Primary resources were analyzed about Stanisław Ciechanowski mainly from depositories of the Section of Special Collection, Stanisław Konopka Main Medical Library Warsaw and Polish bibliograhy of Estreichers at Jagiellonian University.

RESULTS

Professor of anatomic pathology, Stanisław Ciechanowski (1869-1945) was the first to state that chronic inflammation induced overgrowth of parenchymatous and stromal prostate components in course of benign prostatic hyperplasia. Ciechanowski preformed also pioneer and notable studies in the mechanisms of carcinogenesis and classification of cancer in Poland. As one of the major Polish medical editors and a father of Polish modern medical language he was also very prolific author in the field of congenital pathology, sclerosis of pulmonary arteries, endemic goiter, intestinal emphysema, etc. Due to magnitude of autopsies, he preformed, Stanislaw Ciechanowski was a perfect candidate to complete the first edition of several volumes of main Polish handbook on anatomy of a human body after tragic death of professor Adam Bochenek.

CONCLUSIONS

Ciechanowski gained such a high authority, that his opinion was found crucial in prewar Poland in the field of medical publications, but his world-famous achievement was scientific explanation of prostate overgrowth as inflammation induced hyperplasia.

摘要

背景

与巴黎泌尿科医生让·卡西米尔·费利克斯·居永认为进行性动脉粥样硬化是前列腺过度生长和下尿路机械性功能不全的形态学原因的观点相反,克拉科夫的解剖病理学教授斯坦尼斯瓦夫·切哈诺夫斯基(1869 - 1945)首次正确地将前列腺肿大识别为前列腺增生。

方法

主要从华沙斯坦尼斯瓦夫·科诺普卡主医学图书馆特藏部的馆藏以及雅盖隆大学埃斯特赖歇尔波兰文献目录中分析关于斯坦尼斯瓦夫·切哈诺夫斯基的原始资料。

结果

解剖病理学教授斯坦尼斯瓦夫·切哈诺夫斯基(1869 - 1945)是第一个指出在良性前列腺增生过程中慢性炎症会导致前列腺实质和间质成分过度生长的人。切哈诺夫斯基在波兰还进行了癌症发生机制和癌症分类方面的开创性和重要研究。作为波兰主要的医学编辑之一以及波兰现代医学语言之父,他在先天性病理学、肺动脉硬化、地方性甲状腺肿、肠气肿等领域也是一位多产的作者。由于他进行了大量尸检,在亚当·博切内科教授不幸去世后,斯坦尼斯瓦夫·切哈诺夫斯基成为完成波兰人体解剖学几本主要手册第一版的理想人选。

结论

切哈诺夫斯基获得了如此高的权威,以至于他的观点在战前波兰的医学出版物领域被认为至关重要,但他举世闻名的成就是对前列腺过度生长是炎症诱导增生的科学解释。

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