Department of Emergency Medicine, University of British Columbia, British Columbia, Canada.
Department of Emergency Medicine, Vancouver General Hospital, Vancouver, British Columbia, Canada.
Acad Emerg Med. 2019 Jan;26(1):16-22. doi: 10.1111/acem.13454. Epub 2018 Dec 17.
Previous studies of point-of-care ultrasound (POCUS) have reported high sensitivities and specificities for retinal detachment (RD). Our primary objective was to assess the test characteristics of POCUS performed by a large heterogeneous group of emergency physicians (EPs) for the diagnosis of RD.
This was a prospective diagnostic test assessment of POCUS performed by EPs with varying ultrasound experience on a convenience sample of emergency department (ED) patients presenting with flashes or floaters in one or both eyes. After standard ED assessment, EPs performed an ocular POCUS scan targeted to detect the presence or absence of RD. After completing their ED visit, all patients were assessed by a retina specialist who was blinded to the results of the POCUS scan. We calculated sensitivity and specificity with associated exact binomial confidence intervals (CIs) using the retina specialist's final diagnosis as the reference standard.
A total of 30 EPs enrolled 115 patients, with median age of 60 years and 64% female. The retina specialist diagnosed RD in 16 (14%) cases. The sensitivity and specificity of POCUS for detecting RD were 75% (95% CI = 48%-93%) and 94% (95% CI = 87%-98%), respectively. The positive likelihood ratio was 12.4 (95% CI = 5.4-28.3), and negative likelihood ratio was 0.27 (95% CI = 0.11-0.62).
A large heterogeneous group of EPs can perform POCUS with high specificity but only intermediate sensitivity for RD. A negative POCUS scan in the ED performed by a heterogeneous group of providers after a 1-hour POCUS didactic is not sufficiently sensitive to rule out RD in a patient with new-onset flashes or floaters.
之前有关即时超声(POCUS)的研究报告称,视网膜脱离(RD)的检测具有较高的灵敏度和特异性。我们的主要目的是评估由大量不同超声经验的急诊医师(EP)进行的即时超声检查对 RD 的诊断性能。
这是一项前瞻性即时超声检查诊断测试,由具有不同超声经验的 EP 在急诊科就诊的单眼或双眼出现闪光或漂浮物的便利样本患者中进行。在进行标准的急诊科评估后,EP 对眼部进行即时超声扫描,以检测 RD 是否存在。在完成他们的急诊科就诊后,所有患者都由一位对即时超声扫描结果不知情的视网膜专家进行评估。我们使用视网膜专家的最终诊断作为参考标准,计算了灵敏度和特异性,以及相关的精确二项式置信区间(CI)。
共有 30 名 EP 招募了 115 名患者,中位年龄为 60 岁,女性占 64%。视网膜专家诊断出 16 例(14%)RD。即时超声检查对 RD 的敏感性和特异性分别为 75%(95%CI=48%-93%)和 94%(95%CI=87%-98%)。阳性似然比为 12.4(95%CI=5.4-28.3),阴性似然比为 0.27(95%CI=0.11-0.62)。
一个由不同背景的 EP 组成的大型异质群体可以进行即时超声检查,对 RD 具有较高的特异性,但敏感性仅为中等。在接受 1 小时即时超声教学后,由异质群体的提供者在急诊科进行的即时超声阴性检查不能充分敏感地排除新发闪光或漂浮物患者的 RD。