Ye Y, Luo Q, Yu J Q, Zhang J
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Feb;32(3):237-240. doi: 10.13201/j.issn.1001-1781.2018.03.021.
Chronic rhinosinusitis (CRS) is a common disease of otorhinolaryngology head and neck surgery, manifested as nasal-sinus mucosal chronic inflammation. However, the pathogenesis of CRS is not clear. There are studies found that microRNA (miRNA) involved in CRS gene regulation. In this review, we summarize the expression of miRNAs in CRS, with the in-depth study of the role of miRNAs in CRS, and will further elucidate the pathogenesis of CRS.
慢性鼻-鼻窦炎(CRS)是耳鼻咽喉头颈外科的一种常见疾病,表现为鼻窦黏膜的慢性炎症。然而,CRS的发病机制尚不清楚。有研究发现,微小RNA(miRNA)参与了CRS的基因调控。在这篇综述中,我们总结了miRNA在CRS中的表达情况,深入研究了miRNA在CRS中的作用,并将进一步阐明CRS的发病机制。