[慢性鼻-鼻窦炎上皮-间质转化的研究进展]
[Advance in epithelial-mesenchymal transition in chronic rhinosinusitis].
作者信息
Gao Y B, Zhang Y, Zhang L
机构信息
Deparment of Otolaryngology Head and Neck Surgery and Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Deparment of Otolaryngology Head and Neck Surgery and Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing 100005, China.
出版信息
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Mar 7;54(3):231-236. doi: 10.3760/cma.j.issn.1673-0860.2019.03.015.
Chronic rhinosinusitis is a common disease in otorhinolaryngology, which has chronic inflammation in mucosa of nasal cavity and sinus. The mechanisms of chronic rhinosinusitis is still unknown. Recently, some studies show that tissue remodeling has important roles in chronic rhinosinusitis, and as a part of tissue remodeling, epithelial-mesenchymal transition also received high attention. Therefore, this review will summarize the present studies involve epithelial-mesenchymal transition and chronic rhinosinusitis, so as to provide reference for further exploring the pathogenesis of chronic sinusitis.
慢性鼻-鼻窦炎是耳鼻咽喉科的一种常见疾病，其鼻腔和鼻窦黏膜存在慢性炎症。慢性鼻-鼻窦炎的发病机制尚不清楚。最近，一些研究表明组织重塑在慢性鼻-鼻窦炎中起重要作用，作为组织重塑的一部分，上皮-间质转化也受到高度关注。因此，本综述将总结目前涉及上皮-间质转化和慢性鼻-鼻窦炎的研究，为进一步探索慢性鼻窦炎的发病机制提供参考。
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