Department of Psychiatry and Psychotherapy, Medical University of Vienna , Vienna , Austria.
Department of Psychiatry, Psychotherapy & Psychosomatics, University of Zurich , Zurich , Switzerland.
Behav Sleep Med. 2019 Nov-Dec;17(6):713-720. doi: 10.1080/15402002.2018.1469494. Epub 2018 May 18.
: Therapeutic sleep deprivation (SD) is a nonpharmacological treatment that is used most often for depression. The aim of this study was to examine the pattern of use of SD in psychiatric hospitals in Austria, Germany, and Switzerland. : A questionnaire about perceived usage of SD was sent by mail to all 511 psychiatric hospitals in the three countries. Nonresponders were asked to answer the questionnaire by phone. We achieved a response rate of 75.3%. : SD was recommended by 61.3% of all hospitals. Despite this degree of recommendation, nearly two thirds of the psychiatric hospitals had not treated a patient with SD during the last 12 months. Of the respondents, 59.5% considered SD to be indicated for major depressive disorder, 17.7% for bipolar depression, and 7.8% for other indications. SD was administered most frequently in inpatient settings and in combination with other therapies. Total SD (patients kept awake entire night) and partial late SD (patients kept awake in second half of night) were judged equally effective. Of the hospitals, 53.0% reported having seen hypomania and 13.2% manic episodes as side effects (rates do not represent actual incident rates). : The lack of large controlled studies for SD with its different forms of treatment probably still hinders a broader use of the therapy. Therefore, further efforts should be undertaken to provide high-quality scientific evidence for the usage of SD.
治疗性睡眠剥夺(SD)是一种非药物治疗方法,主要用于治疗抑郁症。本研究旨在考察奥地利、德国和瑞士的精神病院 SD 的使用模式。
我们向这三个国家的 511 家精神病院邮寄了一份关于 SD 使用情况的调查问卷。对未回复的医院,我们通过电话请求其回答问卷。我们的回复率为 75.3%。
61.3%的医院推荐使用 SD。尽管推荐程度如此之高,但近三分之二的精神病院在过去 12 个月内未对 SD 患者进行过治疗。在回答者中,59.5%认为 SD 适用于重度抑郁症,17.7%适用于双相情感障碍,7.8%适用于其他适应症。SD 主要在住院治疗和联合其他治疗中使用。完全性 SD(让患者整晚保持清醒)和部分性晚 SD(让患者在夜间后半段保持清醒)被认为同样有效。53.0%的医院报告称看到了轻躁狂,13.2%的医院报告称出现了躁狂发作(这些比率不代表实际的发生率)。
由于缺乏对 SD 及其不同治疗形式的大型对照研究,可能仍然阻碍了该疗法的广泛应用。因此,应进一步努力提供 SD 使用的高质量科学证据。