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通过右胸小切口对骨髓增生异常综合征患者进行微创二尖瓣修复术。

Minimally invasive mitral valve repair via right mini-thoracotomy in patient with myelodysplastic syndrome.

作者信息

Taguchi Takura, Nishi Hiroyuki, Kurose Kimihiro, Horikawa Kohei, Kanazawa Go, Takahashi Toshiki

机构信息

Department of Cardiovascular Surgery, Osaka Police Hospital, 10-31, Kitayama-cho, Tennoji-ku, Osaka, 543-0035, Japan.

出版信息

J Cardiothorac Surg. 2018 May 18;13(1):45. doi: 10.1186/s13019-018-0730-9.

DOI:10.1186/s13019-018-0730-9
PMID:29776423
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5960081/
Abstract

BACKGROUND

Cardiac surgery for myelodysplastic syndrome (MDS) patients is challenging because anemia and neutropenia develop as a result of the syndrome, leading to infection and bleeding tendency during surgery. We report the case of minimally invasive mitral valve repair via a right mini-thoracotomy and perioperative use of granulocyte colony-stimulating factor (G-CSF) in a patient with MDS.

CASE PRESENTATION

A 77-year-old man with myelodysplastic syndrome (MDS) was referred for surgical treatment for mitral valve regurgitation and underwent a minimally invasive mitral valve repair via a right mini-thoracotomy (MICS mitral procedure). On admission, laboratory results showed a leukocyte count of 1500/μL and neutrophils at 190/μL. Prior to surgery, a subcutaneous injection of granulocyte colony-stimulating factor (G-CSF) was given, based on a diagnosis of MDS by a hematologist. The MICS-mitral procedure using artificial chordae and an annular ring prosthesis was completed without requiring re-exploration for bleeding. Postoperatively, a G-CSF injection was administered and transfusion was required. There was no infection complication and the postoperative course was uneventful.

CONCLUSION

A MICS-mitral procedure may be an effective option for MR patients with MDS who require a mitral valve repair to avoid postoperative infection and reduce the incidence of perioperative transfusion.

摘要

背景

对于骨髓增生异常综合征(MDS)患者进行心脏手术具有挑战性,因为该综合征会导致贫血和中性粒细胞减少,进而在手术期间引发感染和出血倾向。我们报告了一例通过右胸小切口进行微创二尖瓣修复并在围手术期使用粒细胞集落刺激因子(G-CSF)治疗的MDS患者。

病例介绍

一名77岁的骨髓增生异常综合征(MDS)男性患者因二尖瓣反流接受手术治疗,通过右胸小切口进行了微创二尖瓣修复术(MICS二尖瓣手术)。入院时,实验室检查结果显示白细胞计数为1500/μL,中性粒细胞为190/μL。手术前,血液科医生根据MDS的诊断给予皮下注射粒细胞集落刺激因子(G-CSF)。使用人工腱索和环形瓣环假体完成了MICS二尖瓣手术,无需因出血而再次开胸探查。术后,给予G-CSF注射并需要输血。没有感染并发症,术后过程顺利。

结论

对于需要进行二尖瓣修复的MDS合并二尖瓣反流患者,MICS二尖瓣手术可能是一种有效的选择,可避免术后感染并降低围手术期输血发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eabf/5960081/3dedcddc1ddb/13019_2018_730_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eabf/5960081/d79a25efc2dd/13019_2018_730_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eabf/5960081/3dedcddc1ddb/13019_2018_730_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eabf/5960081/d79a25efc2dd/13019_2018_730_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eabf/5960081/3dedcddc1ddb/13019_2018_730_Fig2_HTML.jpg

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本文引用的文献

1
Mitral Valve Surgery: Current Minimally Invasive and Transcatheter Options.二尖瓣手术:当前的微创和经导管治疗选择
Methodist Debakey Cardiovasc J. 2016 Jan-Mar;12(1):20-6. doi: 10.14797/mdcj-12-1-20.
2
Aortic valve replacement in a patient with pancytopenia secondary to myelodysplastic syndrome.
J Pak Med Assoc. 2014 Feb;64(2):207-9.
3
Infections in myelodysplastic syndromes.骨髓增生异常综合征中的感染。
Haematologica. 2012 Oct;97(10):1459-70. doi: 10.3324/haematol.2012.063420. Epub 2012 Jun 24.
4
Minimally invasive versus conventional open mitral valve surgery: a meta-analysis and systematic review.微创与传统开放二尖瓣手术:一项荟萃分析与系统评价
Innovations (Phila). 2011 Mar;6(2):84-103. doi: 10.1097/IMI.0b013e3182167feb.
5
Mitral valve repair in a patient with myelodysplastic syndrome.
Ann Thorac Cardiovasc Surg. 2011;17(6):614-7. doi: 10.5761/atcs.cr.10.01643. Epub 2011 Jul 27.
6
Aortic valve replacement and graft replacement of the ascending aorta using deep hypothermic circulatory arrest in a patient with myelodysplastic syndrome.
Ann Thorac Cardiovasc Surg. 2011;17(3):316-9. doi: 10.5761/atcs.cr.10.01540.
7
A rare case of left main coronary stenosis and neutropenia treated with G-CSF prior to CABG.
Thorac Cardiovasc Surg. 2010 Dec;58(8):488-9. doi: 10.1055/s-0030-1250147. Epub 2010 Nov 26.
8
Thrombocytopenia in patients with myelodysplastic syndromes.骨髓增生异常综合征患者的血小板减少症。
Semin Hematol. 2010 Jul;47(3):274-80. doi: 10.1053/j.seminhematol.2010.02.006.
9
Successful replacement of aortic valve using a stentless porcine valve in a patient with myelodysplastic syndrome.
Ann Thorac Cardiovasc Surg. 2008 Apr;14(2):123-5.
10
Aortic valve replacement in a patient with myelodysplastic syndrome and interstitial pneumonia.
Circ J. 2007 Nov;71(11):1826-8. doi: 10.1253/circj.71.1826.