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在一名骨髓增生异常综合征患者中,经右胸小切口二尖瓣修复术期间采用静脉-静脉体外膜肺氧合治疗肺泡出血

Venovenous Extracorporeal Membrane Oxygenation for Alveolar Hemorrhage During Mitral Valve Repair via Right Minithoracotomy in a Patient With Myelodysplastic Syndrome.

作者信息

Nagatsuka Motoki, Asai Tohru, Noguchi Kenichiro, Hama Daisuke, Arai Chishio

机构信息

Department of Cardiovascular Surgery, Shonan Kamakura General Hospital, Kamakura, JPN.

出版信息

Cureus. 2025 Feb 19;17(2):e79320. doi: 10.7759/cureus.79320. eCollection 2025 Feb.

DOI:10.7759/cureus.79320
PMID:40125099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11928235/
Abstract

Cardiac surgery in patients with myelodysplastic syndrome (MDS) is difficult because extracorporeal circulation increases the risk of infection and hemorrhage. We discuss the efficacy of venovenous extracorporeal membrane oxygenation (VV-ECMO) in managing intraoperative alveolar hemorrhage in a patient with MDS undergoing minimally invasive cardiac surgery (MICS) for mitral valve repair. A 76-year-old man with MDS underwent mitral valve repair via right minithoracotomy with standard cardiopulmonary bypass. Left lung hemorrhage developed after declamping of the aorta, and oxygenation support was necessary when the cardiopulmonary bypass was finished, as a bridge until hemostasis. VV-ECMO was established, which involves withdrawing blood from the right femoral vein and returning it via the right internal jugular vein. Platelet transfusion and protamine were administered. Hemostasis was achieved, and the patient was admitted to the intensive care unit without mechanical circulatory support. VV-ECMO proved successful for MICS with hemorrhagic pulmonary complications.

摘要

骨髓增生异常综合征(MDS)患者的心脏手术具有挑战性,因为体外循环会增加感染和出血风险。我们讨论了静脉-静脉体外膜肺氧合(VV-ECMO)在一名接受二尖瓣修复的微创心脏手术(MICS)的MDS患者术中肺泡出血管理中的疗效。一名76岁的MDS男性患者通过右胸小切口经标准体外循环进行二尖瓣修复。主动脉夹闭解除后出现左肺出血,体外循环结束后需要氧合支持作为止血前的过渡。建立了VV-ECMO,即从右股静脉抽血并通过右颈内静脉回输。输注了血小板和鱼精蛋白。实现了止血,患者在没有机械循环支持的情况下被收入重症监护病房。VV-ECMO被证明在伴有出血性肺部并发症的MICS中是成功的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b62/11928235/57398dff7e99/cureus-0017-00000079320-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b62/11928235/960a3d7151a8/cureus-0017-00000079320-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b62/11928235/57398dff7e99/cureus-0017-00000079320-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b62/11928235/960a3d7151a8/cureus-0017-00000079320-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b62/11928235/57398dff7e99/cureus-0017-00000079320-i02.jpg

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本文引用的文献

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Temporary venovenous extracorporeal membrane oxygenation after cardiopulmonary bypass in minimally invasive cardiac surgery via right minithoracotomy.右胸小切口微创心脏手术后体外循环后临时性静脉-静脉体外膜肺氧合
JTCVS Tech. 2023 Apr 25;20:99-104. doi: 10.1016/j.xjtc.2023.04.008. eCollection 2023 Aug.
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Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation.抗中性粒细胞胞质抗体相关性血管炎所致弥漫性肺泡出血的静脉-静脉体外膜肺氧合:起始时不进行全身抗凝。
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Extracorporeal Membrane Oxygenation Support for Antineutrophil Cytoplasmic Antibody-associated Vasculitides: An ELSO Registry Analysis.
体外膜肺氧合支持抗中性粒细胞胞浆抗体相关性血管炎:ELSO 登记分析。
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Minimally invasive mitral valve repair via right mini-thoracotomy in patient with myelodysplastic syndrome.通过右胸小切口对骨髓增生异常综合征患者进行微创二尖瓣修复术。
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Mitral valve repair in a patient with myelodysplastic syndrome.
Ann Thorac Cardiovasc Surg. 2011;17(6):614-7. doi: 10.5761/atcs.cr.10.01643. Epub 2011 Jul 27.
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Platelet dysfunction in myelodysplastic syndromes: a clinicopathological study.骨髓增生异常综合征中的血小板功能障碍:一项临床病理研究。
Int J Hematol. 2002 Oct;76(3):272-8. doi: 10.1007/BF02982798.
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