Glauber Mattia, Miceli Antonio, Canarutto Daniele, Lio Antonio, Murzi Michele, Gilmanov Daniyar, Ferrarini Matteo, Farneti Pier A, Quaini Eugenio L, Solinas Marco
Cardiothoracic department, Fondazione Toscana G. Monasterio, Via Aurelia Sud, Massa, Italy.
J Cardiothorac Surg. 2015 Dec 7;10:181. doi: 10.1186/s13019-015-0390-y.
To report early and long-term outcomes of patients undergoing minimally invasive mitral valve surgery (MIMVS) through right mini-thoracotomy (RT) over a 10-year period.
From September 2003 to December 2013, a total of 1604 consecutive patients underwent MIMVS through RT.
The mean age was 63 ± 13 years, 770 (48 %) patients were female and 218 (13.6 %) had previous cardiac operations. The most predominant pathology was degenerative disease (70 %), followed by functional mitral valve regurgitation (12 %), rheumatic disease (9.4 %), endocarditis (5 %) and prosthetic dysfunction (3.2 %). Mitral valve repair was performed in 1137 (71 %) patients and 476 (29 %) had mitral valve replacement. Direct aortic cannulation was achieved in 1325 (83 %) patients. Among patients with degenerative disease candidate for repair (n = 958), rate of mitral valve repair was 95 %. Repair techniques included annuloplasty (95 %), leafleat resection (63 %), neochordae implantation (16 %) and sliding plasty (11 %). Concomitant procedures included tricuspid valve repair (14.6 %), atrial fibrillation ablation (9.5 %) and atrial septal defect closure (3.2 %). Overall in-hospital mortality was 1.1 %. Thirty-four patients (2.1 %) had conversion to sternotomy. Incidence of stroke was 2 %. Overall survival at 10 years was 88 ± 2 %. Freedom from reoperation at 10 years was 94 ± 2 % for repair and 80 ± 6 % for replacement. Freedom from recurrent mitral regurgitation >3+ at 10 years was 90 ± 3 %.
Minimally invasive mitral valve surgery is a safe and reproducible approach associated with low mortality and morbidity, high rate of mitral valve repair and excellent late results.
报告10年间经右胸小切口行微创二尖瓣手术(MIMVS)患者的早期和长期结果。
2003年9月至2013年12月,共有1604例连续患者经右胸小切口行MIMVS。
平均年龄为63±13岁,770例(48%)为女性,218例(13.6%)曾接受过心脏手术。最主要的病理类型为退行性病变(70%),其次是功能性二尖瓣反流(12%)、风湿性疾病(9.4%)、心内膜炎(5%)和人工瓣膜功能障碍(3.2%)。1137例(71%)患者行二尖瓣修复术,476例(29%)行二尖瓣置换术。1325例(83%)患者成功进行了直接主动脉插管。在退行性病变且适合修复的患者(n = 958)中,二尖瓣修复率为95%。修复技术包括瓣环成形术(95%)、瓣叶切除术(63%)、新腱索植入术(16%)和滑行成形术(11%)。同期手术包括三尖瓣修复术(14.6%)、房颤消融术(9.5%)和房间隔缺损封堵术(3.2%)。总体住院死亡率为1.1%。34例(2.1%)患者转为正中开胸手术。卒中发生率为2%。10年总体生存率为88±2%。修复术后10年再次手术率为94±2%,置换术后为80±6%。10年无>3+级二尖瓣反流复发率为90±3%。
微创二尖瓣手术是一种安全且可重复的方法,死亡率和发病率低,二尖瓣修复率高,远期效果良好。