因呼吸道感染住院儿童中的百日咳博德特氏菌：家庭接触者的临床特征及病原体检测
Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts.
作者信息
Del Valle-Mendoza Juana, Silva-Caso Wilmer, Aguilar-Luis Miguel Angel, Del Valle-Vargas Cristina, Cieza-Mora Erico, Martins-Luna Johanna, Aquino-Ortega Ronald, Silva-Vásquez Andrea, Bazán-Mayra Jorge, Weilg Pablo
机构信息
Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Laboratorio de Biología Molecular, Instituto de Investigación Nutricional, Lima, Peru.
出版信息
BMC Res Notes. 2018 May 18;11(1):318. doi: 10.1186/s13104-018-3405-7.
OBJECTIVE
Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them.
RESULTS
A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.
目的
通过聚合酶链反应（PCR）描述5岁以下因疑似百日咳住院儿童中百日咳博德特氏菌的流行情况，并报告其中最常见的临床特征。
结果
在我们20.5%的样本（18/88）中观察到百日咳博德特氏菌PCR结果呈阳性，其中三分之一来自2至3个月大的婴儿。最常见的症状是阵发性咳嗽（88.9%）、呼吸困难（72.2%）、发绀（77.8%）和发热（50%）。在患百日咳的儿童中，母亲是最常见的有症状携带者（27.8%），其次是叔叔/阿姨（22.2%）。
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