Ithman Muaid, Malhotra Kunal, Bordoloi Meelie, Singh Garima
Department of Psychiatry, University of Missouri-Columbia, Columbia, Missouri.
Department of Nephrology, University of Missouri-Columbia, Columbia, Missouri
Clin Med Res. 2018 Jun;16(1-2):47-49. doi: 10.3121/cmr.2018.1409. Epub 2018 May 18.
Bipolar affective disorder type I imparts significant morbidity and disease burden in the population. It is characterized by occurrence of one or more manic episodes which may be preceded or followed by a depressive or hypomanic phase. About half of these manic episodes are characterized by the presence of psychotic features. The condition is further complicated when the patient has multiple comorbid conditions. We report here the case of a Caucasian woman, aged 66 years, previously diagnosed with Bipolar disorder who developed treatment refractory mania with psychotic feature after being on the immunosuppressive agent, tacrolimus, after kidney transplantation.
I型双相情感障碍给人群带来了显著的发病率和疾病负担。其特征是出现一次或多次躁狂发作，在发作之前或之后可能会有抑郁或轻躁狂阶段。这些躁狂发作中约有一半具有精神病性特征。当患者有多种共病情况时，病情会更加复杂。我们在此报告一例66岁的白人女性病例，该患者先前被诊断为双相情感障碍，在肾移植后使用免疫抑制剂他克莫司后出现了伴有精神病性特征的难治性躁狂。
