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肾移植术后儿童出现与他克莫司相关的伴有精神病症状的躁狂症。

Tacrolimus-associated mania with psychotic symptoms in a child after renal transplant.

作者信息

Gupta Prashant, Singh Jawahar, Mahapatra Ananya, Sharan Pratap

机构信息

Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Natl Med J India. 2018 Sep-Oct;31(5):281-282. doi: 10.4103/0970-258X.261183.

DOI:10.4103/0970-258X.261183
PMID:31267993
Abstract

Tacrolimus is one of the mainstays for post-transplant immunosuppression. A variety of neuropsychiatric adverse effects have been reported above the levels of its therapeutic use. Manic symptoms associated with its use have been rarely reported. We report possibly the first such case in a child post-renal transplantation and discuss the potential neuro-immunological basis of these symptoms.

摘要

他克莫司是移植后免疫抑制的主要药物之一。在其治疗剂量以上已报道了多种神经精神不良反应。与其使用相关的躁狂症状鲜有报道。我们报告了可能是肾移植术后儿童中的首例此类病例，并讨论了这些症状潜在的神经免疫学基础。

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引用本文的文献

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Tacrolimus-induced mania in a patient with nephrotic syndrome.他克莫司诱发的肾病综合征患者躁狂症
Indian J Pharmacol. 2020 Nov-Dec;52(6):531-532. doi: 10.4103/ijp.IJP_710_20.
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New-onset Psychosis in an Immunosuppressed Patient With Kidney Transplantation: An Educational Case Report.一名肾移植免疫抑制患者的新发精神病：一份教育性病例报告。
Can J Kidney Health Dis. 2020 Aug 4;7:2054358120947210. doi: 10.1177/2054358120947210. eCollection 2020.