Mamani Mojgan, Majzoobi Mohammad Mehdi, Keramat Fariba, Varmaghani Nesa, Moghimbeigi Abbas
Department of Infectious Diseases, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran.
J Res Health Sci. 2018 Feb 10;18(1):e00406.
Brucellosis is a zoonotic disease caused by Brucella species via infected domestic animals. In endemic areas, certain occupations such as veterinarians, butchers, and slaughterhouse workers are considered high risk regarding brucellosis. We evaluated the seroprevalence of brucellosis in high-risk occupations in Hamadan, West of Iran.
a cross-sectional study.
Overall, 218 participants from 2014 to 2015 were enrolled. A questionnaire including demographic data, length of employment, and using personal protective equipment was completed for each of them. Then, blood samples were taken and sent to Hamadan Health Center to be tested by Wright or standard tube agglutination (STA). In addition, samples with positive Wright test were examined by 2-mercaptoethanol (2ME) test. Then, seropositive participants were evaluated for clinical manifestations of brucellosis. All collected data were analyzed by SPSS ver. 16.
The mean age of the participants was 42.79±11.16 yr and all seropositive cases were male. Based on Wright ≥1/80 and 2ME ≥1/40, seroprevalence of brucellosis was 13.3% and 12.3%, respectively. The use of personal protective equipment was low among individuals with or without brucellosis. Myalgia, fatigue, back pain, joint pain, night sweats, fever, malaise, and headache were common symptoms in seropositive cases. Moreover, 20.6% of the seropositive participants were asymptomatic.
High prevalence of brucellosis in these occupational groups and symptomatic disease in significant numbers of them, so periodic clinical examinations in these groups seems to be essential for brucellosis surveillance system.
布鲁氏菌病是一种由布鲁氏菌属通过感染家畜引起的人畜共患病。在流行地区，某些职业如兽医、屠夫和屠宰场工人被认为感染布鲁氏菌病的风险较高。我们评估了伊朗西部哈马丹高危职业人群中布鲁氏菌病的血清流行率。
一项横断面研究。
2014年至2015年共纳入218名参与者。为每位参与者填写一份包括人口统计学数据、工作年限和使用个人防护设备情况的问卷。然后采集血样并送至哈马丹健康中心，采用wright试验或标准试管凝集试验（STA）进行检测。此外，wright试验阳性的样本用2-巯基乙醇（2ME）试验进行检测。然后，对血清学阳性的参与者进行布鲁氏菌病临床表现的评估。所有收集的数据均采用SPSS 16.0版进行分析。
参与者的平均年龄为42.79±11.16岁，所有血清学阳性病例均为男性。根据wright试验≥1/80和2ME试验≥1/40，布鲁氏菌病的血清流行率分别为13.3%和12.3%。无论是否感染布鲁氏菌病，个人防护设备的使用率都较低。血清学阳性病例中常见的症状有肌痛、疲劳、背痛、关节痛、盗汗、发热、不适和头痛。此外，20.6%的血清学阳性参与者无症状。
这些职业群体中布鲁氏菌病的患病率较高，且相当一部分人有症状性疾病，因此对这些群体进行定期临床检查似乎对布鲁氏菌病监测系统至关重要。
