Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, T6G 2B7, Canada.
Department of Physics, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Biomech Model Mechanobiol. 2018 Oct;17(5):1269-1279. doi: 10.1007/s10237-018-1025-8. Epub 2018 May 18.
The fundamental ultrasonic guided modes are consistently observed in long bones ex vivo and in vivo. However, the responses of ultrasonic guided waves to the changes of cortical thickness, cortical elastic parameters, and thickness of the overlying soft tissues are not comprehensively understood. This paper systematically presents a sensitivity analysis of leaky Lamb modes to the geometry and material characteristics of layered bone model by means of semi-analytical finite element modeling. The stratified bone model is consisted of a transversely isotropic cortex with an overlying soft tissue and underlying marrow. The study is important as it offers guidance to the parameter inversion process about the optimal selection of guided modes and regions of sensitivity for better inversion results.
在长骨的离体和活体中，始终可以观察到基本的超声导波模式。然而，超声导波对皮质厚度、皮质弹性参数和覆盖软组织厚度变化的响应尚未得到全面的理解。本文通过半解析有限元建模，系统地研究了层状骨模型的漏模兰姆波对几何形状和材料特性的灵敏度。分层骨模型由具有覆盖软组织和下方骨髓的各向异性皮质组成。该研究非常重要，因为它为参数反演过程提供了指导，有助于选择最佳的导波模式和灵敏度区域，以获得更好的反演结果。
