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带或不带结缔组织移植物的冠向推进瓣治疗上颌单个牙龈退缩的长期预后稳定性的预测因素:一项随机对照临床试验的 9 年结果。

Predictor factors for long-term outcomes stability of coronally advanced flap with or without connective tissue graft in the treatment of single maxillary gingival recessions: 9 years results of a randomized controlled clinical trial.

机构信息

Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

Foundation IRCCS Ca' Granda Polyclinic, Milan, Italy.

出版信息

J Clin Periodontol. 2018 Sep;45(9):1107-1117. doi: 10.1111/jcpe.12932. Epub 2018 Aug 20.

Abstract

AIM

To assess the clinical outcomes 9 years after the surgical treatment of single maxillary gingival recessions and identify predictors for long-term gingival margin stability.

MATERIALS AND METHODS

Twenty-five gingival recessions (Miller Class I and II) were randomly treated with Coronally Advanced Flap (CAF) plus Connective Tissue Graft (CTG) or CAF alone. Outcomes included complete root coverage (CRC), recession reduction (REC), keratinized tissue (KT) gain and dentin hypersensitivity, and were evaluated at 6 months, 1 and 9 years. Multilevel analysis was performed to identify predictors for long-term gingival margin stability.

RESULTS

Baseline gingival recession was 2.4 ± 0.8 mm and 2.4 ± 1.0 mm in the CAF + CTG and in the CAF-treated sites, respectively (p = 0.693). The chance to gain and preserve CRC over time is equal to 70% in the CAF + CTG group (Relative Risk [RR] = 1.70, 95% CI [0.84-3.45]; adjusted RR = 1.48, 95% CI [0.61-3.62]). Using the CTG, an increase in KT was recorded 9 years after the surgery (p = 0.019). An OR of 0.12 (p = 0.022) of not achieving CRC was observed in cases with non-carious cervical lesions (NCCL) compared to cases without NCCL.

CONCLUSION

Both treatment modalities demonstrated stability over time. Additional use of CTG provided a greater increase in KT. The presence of NCCL negatively affected CRC and REC.

摘要

目的

评估单上颌牙龈退缩手术后 9 年的临床效果,并确定长期牙龈边缘稳定性的预测因素。

材料和方法

随机选择 25 例(Miller 分类 I 和 II)牙龈退缩患者,分别采用冠向推进瓣(CAF)联合结缔组织移植(CTG)或 CAF 单独治疗。结果包括完全根覆盖(CRC)、退缩减少(REC)、角化组织(KT)增加和牙本质过敏,并在术后 6 个月、1 年和 9 年进行评估。采用多水平分析方法确定长期牙龈边缘稳定性的预测因素。

结果

基线时 CAF+CTG 组和 CAF 组的牙龈退缩分别为 2.4±0.8mm 和 2.4±1.0mm(p=0.693)。CAF+CTG 组获得和保持 CRC 的机会随着时间的推移而增加,其相对风险(RR)为 1.70(95%CI [0.84-3.45]);调整后的 RR 为 1.48(95%CI [0.61-3.62])。术后 9 年,使用 CTG 记录到 KT 增加(p=0.019)。与无非龋性颈病变(NCCL)的病例相比,有 NCCL 的病例获得 CRC 的几率降低(OR 为 0.12,p=0.022)。

结论

两种治疗方法均显示出随时间的稳定性。额外使用 CTG 可使 KT 增加更多。非龋性颈病变的存在对 CRC 和 REC 有负面影响。

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