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上皮下结缔组织移植加冠向推进瓣治疗上颌单个退缩型缺损的 20 年长期疗效评价。

Long-term evaluation (20 years) of the outcomes of subepithelial connective tissue graft plus coronally advanced flap in the treatment of maxillary single recession-type defects.

机构信息

Tuscany Academy of Dental Research (ATRO), Florence, Italy.

Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.

出版信息

J Periodontol. 2018 Nov;89(11):1290-1299. doi: 10.1002/JPER.17-0619. Epub 2018 Aug 10.

Abstract

BACKGROUND

Subepithelial connective tissue graft with coronally advanced flap (SCTG + CAF) has been considered the best and most predictable root coverage procedure. Thus, the aims of this study are two-fold: 1) to evaluate the long-term outcomes following SCTG + CAF in the treatment of gingival recessions (GR) and 2) to explore the influence of several tooth/patient-related factors on the stability of gingival margin at 1 year and at 5,10, 15, and 20 years after surgery.

METHODS

Forty-five patients with 45 maxillary GR (Miller's Class I or III) were treated with SCTG + CAF in a private practice between 1990 and 1997. Recession depth (RD), probing depth (PD), keratinized tissue (KT) width and patient/tooth-associated variables were recorded for each GR at baseline, 1, 5, 10, 15, and 20 years after surgery. Parametric, non-parametric, and logistic regression statistics were used throughout the study.

RESULTS

A total of 21 Class I (44.67%) and 24 Class III (53.33%) GR were treated. Considering all the 45 GR, statistically significant improvements were found for RD in all evaluations (P < 0.05) compared with baseline data. Over the course of the study, mean root coverage (MRC) decreased from 74.23% (1 year) to 67.69% (20 years). Within maxillary Class I defects, complete root coverage (CRC) at 1-year follow-up was 57.14% (n = 12) and 47.62% (n = 10) at the end of study period, whereas MRC decreased from 82.37% to 77.62%, respectively. Within maxillary Class III recessions, CRC of 20.83% (n = 5) was found at both the 1-year and the 20-year follow-ups. On the other hand, MRC decreased from 66.55% to 58.18%, respectively. The results of logistic regression analysis showed that the achievement of CRC was associated with sites not presenting interdental tissue loss (i.e., Class I, odds ratio: 5.031, P = 0.024), whereas GR recurrence appeared associated with sites with attached KT < 2 mm (i.e., 5-, 10-, 15- and 20-year follow-ups), to teeth presenting root steps (i.e., 10- and 20-year follow-ups), and smoking (i.e., 15-year follow-up).

CONCLUSIONS

Positive RD reduction and KT improvements achieved by SCTG + CAF at short-term may be preserved long-term with the majority of the treated sites not displaying relapse of the gingival margin. Teeth lacking a minimal 2-mm width of attached KT and presenting non-carious cervical lesions were more prone to develop an apical shift of the gingival margin during a 20-year follow-up period.

摘要

背景

带冠向推进瓣的黏膜下结缔组织移植术(SCTG+CAF)已被认为是最佳和最可预测的根覆盖程序。因此,本研究的目的有两个:1)评估 SCTG+CAF 治疗牙龈退缩(GR)的长期效果,2)探讨若干牙齿/患者相关因素对术后 1 年、5 年、10 年、15 年和 20 年时牙龈边缘稳定性的影响。

方法

1990 年至 1997 年间,在一家私人诊所,45 名上颌 GR(Miller 分类 I 或 III)患者接受了 SCTG+CAF 治疗。在基线、术后 1、5、10、15 和 20 年,对每个 GR 的龈退缩深度(RD)、探诊深度(PD)、角化组织(KT)宽度和患者/牙齿相关变量进行记录。本研究全程采用参数、非参数和逻辑回归统计。

结果

共治疗了 21 个 Class I(44.67%)和 24 个 Class III(53.33%)GR。考虑到所有 45 个 GR,与基线数据相比,所有评估的 RD 均有显著改善(P<0.05)。在研究过程中,平均根覆盖(MRC)从术后 1 年的 74.23%降至 20 年的 67.69%。在上颌 Class I 缺损中,1 年随访时完全根覆盖(CRC)为 57.14%(n=12),研究结束时为 47.62%(n=10),而 MRC 分别从 82.37%降至 77.62%。在上颌 Class III 退缩中,1 年和 20 年随访时,CRC 分别为 20.83%(n=5)和 20.83%(n=5)。另一方面,MRC 分别从 66.55%降至 58.18%。逻辑回归分析结果显示,CRC 的获得与未出现牙间组织丧失的部位(即 Class I,优势比:5.031,P=0.024)有关,而 GR 复发似乎与附着 KT<2mm 的部位(即 5 年、10 年、15 年和 20 年随访)、存在根面台阶的牙齿(即 10 年和 20 年随访)和吸烟(即 15 年随访)有关。

结论

SCTG+CAF 在短期内可实现 RD 的显著减少和 KT 的改善,在大多数治疗部位,其长期效果可保持牙龈边缘无复发。缺乏最小 2mm 附着 KT 的牙齿和存在非龋性颈病变的牙齿在 20 年随访期间更易发生牙龈边缘的根尖移位。

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