Mai Trinh, Woo Michael Y, Boles Kim, Jetty Prasad
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; Department of Emergency Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Ann Vasc Surg. 2018 Oct;52:15-21. doi: 10.1016/j.avsg.2018.03.015. Epub 2018 May 17.
The use of point-of-care ultrasound (POCUS) has become increasingly prevalent in medical practice as a non-invasive tool for focused bedside diagnosis. Consequently, some medical schools have begun implementing POCUS training as a standard in their medical school curriculum. The feasability and value of introducing POCUS training at the medical student level to screen for abdominal aortic aneurysms (AAA) should be explored. Given this, the objective of our study was to determine the test characteristics of point-of-care ultrasonography performed by a medical student versus physical examination by vascular surgeons compared to a gold standard reference scan for the detection of AAAs.
We conducted a prospective, observer-blinded study recruiting patients from an outpatient vascular surgery clinic. Participants were screened for AAAs by standardized physical examination by a blinded vascular surgeon, followed by a POCUS examination by a blinded medical student. The student underwent prior training by a vascular sonographer and emergency physician on 60 patients (16 were supervised). Ultrasonography was used to visualize and measure the proximal, mid, and distal aortic diameters. The maximal aortic diameter was noted and compared with measurements obtained by the reference scan (computed tomography scan or vascular sonographer-performed ultrasound). Reference scans were completed within 3 months of the recruitment visit.
A total of 57 patients were enrolled over a 5-month period between October 2015 and March 2016. Mean age of recruited patients was 71 years, and 61% were male. Mean body mass index was 27.9 ± 4.3, and mean waist-to-hip ratio was 0.96 ± 0.10. Sixteen AAAs were detected by the reference scan, with an average maximal aortic diameter of 44.9 mm. Physical examination by a vascular surgeon detected 11 of 16 AAAs with 2 false positives (sensitivity and specificity of 66.7% [95% confidence interval [CI], 38.4-88.2] and 94.4% [95% CI, 81.3-99.3], respectively). POCUS detected 15 of 16 AAAs (sensitivity and specificity of 93.3% [95% CI, 68.1-99.8] and 100% [95% CI, 88.4-100], respectively). Seven of the 64 POCUS scans were indeterminate (>1 cm of the aorta was not visualized). Average time to conduct the physical examination was 35 sec versus 4.0 min for point-of-care ultrasonography. There was a strong linear correlation (R = 0.95) between maximal aortic diameter measured by point-of-care ultrasonography versus reference scan with a mean absolute difference of 2.6 mm.
Point-of-care ultrasonography performed by a medical student is highly accurate and more effective in detecting AAAs than physical examination by vascular surgeons. The introduction of POCUS training at the medical student level and its wide-scale implementation as an extension to physical examination may lead to improved detection of AAAs.
作为一种用于床边聚焦诊断的非侵入性工具,即时超声检查(POCUS)在医学实践中越来越普遍。因此,一些医学院校已开始将POCUS培训作为其医学院课程的标准内容。应探索在医学生阶段引入POCUS培训以筛查腹主动脉瘤(AAA)的可行性和价值。鉴于此,我们研究的目的是确定医学生进行的即时超声检查与血管外科医生进行的体格检查相比,相对于检测AAA的金标准参考扫描的测试特征。
我们进行了一项前瞻性、观察者盲法研究,从门诊血管外科诊所招募患者。由一位盲法血管外科医生通过标准化体格检查对参与者进行AAA筛查,随后由一位盲法医学生进行POCUS检查。该学生之前在一位血管超声检查医师和一位急诊医师的指导下对60例患者进行了培训(其中16例有监督)。使用超声检查来可视化和测量主动脉近端、中部和远端的直径。记录最大主动脉直径,并与参考扫描(计算机断层扫描或血管超声检查医师进行的超声检查)获得的测量值进行比较。参考扫描在招募就诊后的3个月内完成。
在2015年10月至2016年3月的5个月期间,共招募了57例患者。招募患者的平均年龄为71岁,61%为男性。平均体重指数为27.9±4.3,平均腰臀比为0.96±0.10。参考扫描检测出16例AAA,平均最大主动脉直径为44.9mm。血管外科医生进行的体格检查在16例AAA中检测出11例,有2例假阳性(敏感性和特异性分别为66.7%[95%置信区间(CI),38.4 - 88.2]和94.4%[95%CI,81.3 - 99.3])。POCUS在16例AAA中检测出15例(敏感性和特异性分别为93.3%[95%CI,68.1 - 99.8]和100%[95%CI,88.4 - 100])。64次POCUS扫描中有7次结果不确定(主动脉>1cm未被可视化)。进行体格检查的平均时间为35秒,而即时超声检查为4.0分钟。即时超声检查测量的最大主动脉直径与参考扫描之间存在很强的线性相关性(R = 0.95),平均绝对差值为2.6mm。
医学生进行的即时超声检查在检测AAA方面比血管外科医生进行的体格检查具有更高的准确性和有效性。在医学生阶段引入POCUS培训并将其作为体格检查的扩展进行广泛实施,可能会提高AAA的检测率。