Hyytiäinen Heli K, Mölsä Sari H, Junnila Jouni J T, Laitinen-Vapaavuori Outi M, Hielm-Björkman Anna K
Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Oy 4Pharma Ltd, Helsinki, Finland.
Vet Rec. 2018 Sep 15;183(10):324. doi: 10.1136/vr.104588. Epub 2018 May 19.
This study aimed at developing a quantitative testing battery for dogs' stifle functionality, as, unlike in human medicine, currently none is available in the veterinary field. Forty-three dogs with surgically treated unilateral cranial cruciate ligament rupture and 21 dogs with no known musculoskeletal problems were included. Eight previously studied tests: compensation in sitting and lying positions, symmetry of thrust in hindlimbs when rising from lying and sitting, static weight bearing, stifle flexion and extension and muscle mass symmetry, were summed into the Finnish Canine Stifle Index (FCSI). Sensitivities and specificities of the dichotomised FCSI score were calculated against orthopaedic examination, radiological and force platform analysis and a conclusive assessment (combination of previous). One-way analysis of variance (ANOVA)was used to evaluate FCSI score differences between the groups. Cronbach's alpha for internal consistency was calculated. The range of the index score was 0-263, with a proposed cut-off value of 60 between 'adequate' and 'compromised' functional performance. In comparison to the conclusive assessment, the sensitivity and specificity of the FCSI were 90 per cent and 90.5 per cent, respectively. Cronbach's alpha for internal reliability of the FCSI score was 0.727. An estimate of the surgically treated and control dogs' FCSI scores were 105 (95 per cent CI 93 to 116) and 20 (95 per cent CI 4 to 37), respectively. The difference between the groups was significant (P<0.001).
本研究旨在开发一套用于评估犬膝关节功能的定量测试组合，因为与人类医学不同，目前兽医领域尚无此类测试。研究纳入了43只接受过单侧颅侧十字韧带破裂手术治疗的犬以及21只无已知肌肉骨骼问题的犬。将八项先前研究过的测试：坐卧姿势的代偿、从躺卧和坐姿起身时后肢推力的对称性、静态负重、膝关节屈伸以及肌肉质量对称性，汇总成芬兰犬膝关节指数（FCSI）。针对骨科检查、放射学和测力平台分析以及最终评估（上述各项的综合），计算了二分法FCSI评分的敏感性和特异性。采用单因素方差分析（ANOVA）来评估两组之间的FCSI评分差异。计算了用于评估内部一致性的Cronbach's α系数。该指数评分范围为0至263，建议在功能表现“良好”和“受损”之间的临界值为60。与最终评估相比，FCSI的敏感性和特异性分别为90%和90.5%。FCSI评分的内部可靠性的Cronbach's α系数为0.727。接受手术治疗的犬和对照犬的FCSI评分估计分别为105（95%置信区间93至116）和20（95%置信区间4至37）。两组之间的差异具有显著性（P<0.001）。
