Suppr超能文献

50 岁以上患者行冠状动脉旁路移植术(CABG)联合肺切除术治疗肺癌。

Combined Coronary Artery Bypass Graft (CABG) Surgery and Lung Resection for Lung Cancer in Patients More than 50 Years-of-Age.

机构信息

Department of Cardiology, Shanghai Tenth Peoples' Hospital, Tongji University School of Medicine, Shanghai, China (mainland).

The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, Chile.

出版信息

Med Sci Monit. 2018 May 20;24:3307-3314. doi: 10.12659/MSM.907545.

Abstract

BACKGROUND The co-existence of coronary heart disease (CHD) and lung cancer is increasing in an increasingly aging population. The aim of this study was to evaluate patient outcome from combined off-pump coronary artery bypass graft (CABG) surgery and lung resection in patients more than 50 years-of-age. MATERIAL AND METHODS A retrospective clinical study of 23 patients with a mean age of 70.2±8.4 years (range, 51-86 years) included 18 men and five women with CHD and lung cancer who underwent a single operation with combined off-pump CABG surgery and lung resection, for non-small cell lung cancer (NSCLC) (n=22) and small cell lung cancer (n=1). Surgical approaches included: median sternotomy in six patients; left lateral thoracotomy in nine patients; a median sternotomy in three patients; median sternotomy combined with thoracoscopic lobectomy in five patients. RESULTS In the retrospective study of 23 patients, there were no deaths and no new cases of myocardial infarction (MI) in the immediate perioperative period. During the follow-up period, six patients died from lung cancer metastasis or recurrence; one patient died of acute renal failure; and one patient died from the effects of chemotherapy. The remaining 15 patients underwent postoperative follow-up for between 3-79 months with no deaths and no new cases of MI. CONCLUSIONS For patients who are more than 50 years-of-age and who have CHD and lung cancer, a single combined operation that includes off-pump CABG and lung resection can be safe and effective.

摘要

背景

在人口老龄化日益加剧的情况下,冠心病(CHD)和肺癌同时存在的情况越来越多。本研究旨在评估 50 岁以上患者行非体外循环冠状动脉旁路移植术(CABG)联合肺切除术的患者的预后。

材料和方法

回顾性临床研究纳入 23 例平均年龄 70.2±8.4 岁(51-86 岁)的 CHD 合并肺癌患者,包括 18 名男性和 5 名女性,行单一手术联合非体外循环 CABG 术和肺切除术,治疗非小细胞肺癌(NSCLC)(n=22)和小细胞肺癌(n=1)。手术入路包括:6 例患者行正中开胸术;9 例患者行左外侧开胸术;3 例患者行正中开胸术;5 例患者行正中开胸术联合胸腔镜肺叶切除术。

结果

在 23 例回顾性研究患者中,围手术期内无死亡和新发心肌梗死(MI)病例。随访期间,6 例患者死于肺癌转移或复发;1 例患者死于急性肾衰竭;1 例患者死于化疗影响。其余 15 例患者术后随访 3-79 个月,无死亡和新发 MI 病例。

结论

对于 50 岁以上患有 CHD 和肺癌的患者,行非体外循环 CABG 联合肺切除术的单一联合手术是安全有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8d9/5989628/a09d9990016e/medscimonit-24-3307-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验